Matching Items (17)
Description
Leo Kanner first described autism in his 1943 article in Nervous Child titled "Autistic Disturbances of Affective Contact". Throughout, he describes the eleven children with autism in exacting detail. In the closing paragraphs, the parents of autistic children are described as emotionally cold. Yet, he concludes that the condition as he described it was innate. Since its publication, his observations about parents have been a source of controversy surrounding the original definition of autism.
Thus far, histories about autism have pointed to descriptions of parents of autistic children with the claim that Kanner abstained from assigning them causal significance. Understanding the theoretical context in which Kanner's practice was embedded is essential to sorting out how he could have held such seemingly contrary views simultaneously.
This thesis illustrates that Kanner held an explicitly descriptive frame of reference toward his eleven child patients, their parents, and autism. Adolf Meyer, his mentor at Johns Hopkins, trained him to make detailed life-charts under a clinical framework called psychobiology. By understanding that Kanner was a psychobiologist by training, I revisit the original definition of autism as a category of mental disorder and restate its terms. This history illuminates the theoretical context of autism's discovery and has important implications for the first definition of autism amidst shifting theories of childhood mental disorders and the place of the natural sciences in defining them.
Thus far, histories about autism have pointed to descriptions of parents of autistic children with the claim that Kanner abstained from assigning them causal significance. Understanding the theoretical context in which Kanner's practice was embedded is essential to sorting out how he could have held such seemingly contrary views simultaneously.
This thesis illustrates that Kanner held an explicitly descriptive frame of reference toward his eleven child patients, their parents, and autism. Adolf Meyer, his mentor at Johns Hopkins, trained him to make detailed life-charts under a clinical framework called psychobiology. By understanding that Kanner was a psychobiologist by training, I revisit the original definition of autism as a category of mental disorder and restate its terms. This history illuminates the theoretical context of autism's discovery and has important implications for the first definition of autism amidst shifting theories of childhood mental disorders and the place of the natural sciences in defining them.
ContributorsCohmer, Sean (Author) / Hurlbut, James B (Thesis advisor) / Maienschein, Jane (Committee member) / Laubichler, Manfred (Committee member) / Arizona State University (Publisher)
Created2014
Description
Environmental and genetic factors contribute to schizophrenia etiology, yet few studies have demonstrated how environmental stimuli impact genes associated with the disorder. Immediate early genes (IEGs) are of great interest to schizophrenia research because they are activated in response to physiological stress from the environment, and subsequently regulate the expression of downstream genes that are essential to neuropsychiatric function. An IEG, early growth response 3 (EGR3) has been identified as a main gene involved in a network of transcription factors implicated in schizophrenia susceptibility. The serotonin 2A receptor (5-HT2AR) seems to play an important role in schizophrenia and the dysfunction of the 5-HT2AR encoding gene, HTR2A, within the prefrontal cortex (PFC) contributes to multiple psychiatric illnesses including schizophrenia. EGR3's role as a transcription factor that is activated by environmental stimuli suggests it may regulate Htr2a transcription in response to physiological stress, thus affecting 5-HT2AR function in the prefrontal cortex (PFC). The aim of this study was to examine the relationship between Egr3 activation and Htr2a expression after an environmental stimulus. Sleep deprivation is an acute physiological stressor that activates Egr3. Therefore to examine the relationship between Egr3 and Htr2a expression after an acute stress, wild type and Egr3 knockout mice that express EGFP under the control of the Htr2a promoter were sleep deprived for 8 hours. We used immunohistochemistry to determine the location and density of Htr2a-EGFP expression after sleep deprivation and found that Htr2a-EGFP expression was not affected by sex or subregions of the PFC. Additionally, Htr2a-EGFP expression was not affected by the loss of Egr3 or sleep deprivation within the PFC. The LPFC subregions, layers V and VI showed significantly more Htr2a-EGFP expression than layers I-III in all animals for both sleep deprivation and control conditions. Possible explanations for the lack of significant effects in this study may be the limited sample size or possible biological abnormalities in the Htr2a-EGFP mice. Nonetheless, we did successfully visualize the anatomical distribution of Htr2a in the prefrontal cortex via immunohistochemical staining. This study and future studies will provide insight into how Egr3 activation affects Htr2a expression in the PFC and how physiological stress from the environment can alter candidate schizophrenia gene function.
ContributorsSabatino, Alissa Marie (Author) / Gallitano, Amelia (Thesis director) / Hruschka, Daniel (Thesis director) / Maple, Amanda (Committee member) / Barrett, The Honors College (Contributor)
Created2014-05
Description
This paper investigates how stress in parents is affected by their child's Attention-Deficit/Hyperactivity Disorder (ADHD). The purpose of this paper is to identify common stressors for parents of children with ADHD, as well as to determine what parents need from healthcare providers to mediate this stress. A survey was developed to identify sources of stress, consequences of parental stress, parental coping methods, resources provided by their healthcare provider that have been helpful, along with what they feel that they need from their healthcare providers in order to better support themselves and their family. Participants were composed of members of Facebook support groups for parents of children with ADHD. Major findings of this study include: parents experience the most stress when dealing with their child's oppositional and aggressive behaviors; parents frequently experience disruption in their marital relationship; and parents perceive that they receive little health care resources that are helpful for themselves, their child, and their family overall.
ContributorsHui, Natasha Faith (Author) / Sayles, Judy (Thesis director) / Beals, Jacqueline (Committee member) / Caterino, Linda (Committee member) / Arizona State University. College of Nursing & Healthcare Innovation (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The Arizona healthcare system is changing and although its effects can be seen in almost every realm of the medical field, psychiatry is a specialty that is still experiencing hardship. There are scarce resources available for the ever-growing and struggling patient pool, especially in rural areas and minority populations. A comorbid cycle of untreated psychiatric illness contributes to the burden on emergency department and primary care medicine, as well as homelessness, crime, and suicide within the state. Arizona currently has a dismal spot in the rankings for American states with appropriate access to psychiatric resources, leaving many who need treatment without it. Compared to states with similar populations who are at the top of these rankings, Arizona spends more government money for behavioral health services, indicating a disparity in productivity and questioning monetary waste. Demographic statistics and other relevant scientific literature reveals that Arizona's psychiatric system lacks appropriate structure, and is failing the mental health care system both in monetary and societal constructs. These issues highlight the need for remedies and identify areas for future reform. Recommendations on such reform include permanent change in legislation and department models to improve crisis ward work, communication and networking during transition of care, integration of and access to continuum of care, and community education. They also include creating incentive and certification programs within the state in order to increase the number of available providers, especially in rural areas. These recommendations are directed to specifically reduce the burden of mental illness on emergency medical services, increase productivity, and decrease chronic untreated mental disease and monetary waste.
ContributorsHarding, Calen LeMay (Author) / Perez, Marisol (Thesis director) / Neal, Tess (Committee member) / Department of Psychology (Contributor) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
The American Psychiatric Association's Diagnostic and Statistical Manual, the official guidebook to psychiatric diagnosis in America, currently exempts the recently bereaved from being diagnosed with depression unless their experiences are marked by feelings of extreme worthlessness, significant functional impairment, psychotic symptoms, psychomotor retardation, or suicidal ideation. Ordinary symptoms of depression, such as sleeplessness or loss of appetite, are considered healthy, functional emotional responses to the loss of a loved one. The bereavement exemption is slated for removal in the upcoming fifth edition of the Diagnostic and Statistical Manual, functionally redefining the emotional distress of bereavement as a psychiatric disorder. This study employs genealogical analysis to expose the multiplicity of forces that shape modern psychiatry and the ways that the redefinition of depression functions strategically in the social negotiation of truth and power. Under the guise of etiological and prescriptive neutrality, the redefinition of depression promotes a deeply biological model of psychiatric disorder, a medicalized understanding of human emotion, and a pharmacological approach to the treatment of emotional distress. Through genealogical analysis, this project seeks to enable informed, meaningful ethico-political responses to these developments.
ContributorsMeeth, John (Author) / Edson, Belle (Thesis advisor) / Palazzolo, Kellie (Thesis advisor) / Quinlivan, Raena (Committee member) / Arizona State University (Publisher)
Created2011
Description
It is not necessarily concerning that it is harder for some to conform to the law until it brings up the issue of insanity. The insanity defense, though controversial, is inherently retributive in that punishing the mentally ill is not blameworthy. As ill-suited subjects for blame, mentally ill persons lack the cognitive reasoning skills necessary to be held legally accountable. Exculpating the mentally ill is not only retributive, but also deeply intuitive, evidenced by how many mentally ill persons seem "odd or crazy" to the average person. Finally, of all the tests used to determined insanity, the Federal Test of 1984 most successfully renders the insanity defense narrow enough to minimize abuse, allows for expert testimony, and calls for a cognitive interpretation of insanity.
ContributorsGilman, Lindsey Erin (Author) / Sigler, Mary (Thesis director) / Murphy, Jeffrie (Committee member) / Botham, Thad (Committee member) / Barrett, The Honors College (Contributor) / School of Historical, Philosophical and Religious Studies (Contributor) / School of Social Transformation (Contributor)
Created2013-05
Description
Previous studies suggest an association between depression and anxiety in childhood and adolescence and increased risk for cardiovascular disease later in life. The aim of the present study was to test whether depression and anxiety symptoms in young adulthood were associated with retinal vessel diameter, a subclinical marker of cardiovascular disease. We further tested whether associations for depression were similar to associations for anxiety. Participants completed questionnaires about their depression and anxiety symptoms and underwent retinal imaging. Retinal vessel diameter was assessed using computer software. Results showed no association between depression or anxiety symptoms and retinal vessel diameter, suggesting that retinal vessel diameter may not signal subclinical cardiovascular risk in young adults with symptoms of depression and anxiety.
ContributorsGandee, Katherine Marie (Author) / Meier, Madeline (Thesis director) / Perez, Marisol (Committee member) / Infurna, Frank (Committee member) / Department of Psychology (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
Description
Pediatric anxiety disorders are highly prevalent and while pharmacological intervention seems to be an effective treatment, the validity of reported adverse side effects remains unclear. <br/><br/>Objective: To analyze the nature of evidence regarding adverse side effects in the pharmacological treatment of pediatric anxiety disorders. <br/><br/>Approach: A search using Google Scholar, PubMed, and PsychInfo was conducted for meta-analyses of pharmacological treatment of pediatric anxiety disorders as well as randomized controlled trials. The focus was on adverse events.<br/><br/>Results and Conclusion: Reportings of a limited number of adverse events were found among resources available to clinician and patient informed sources to inform pharmacological treatment of pediatric anxiety disorders. Only a small fraction of adverse side effects were found in the research literature. This finding raises concerns about making informed decisions to treat pediatric anxiety disorders with pharmacotherapy.
ContributorsMartin, Mark (Co-author) / Reyes, Trevin (Co-author) / Whooley, Max (Co-author) / Pina, Armando (Thesis director) / Benoit, Renee (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
The ethics of forensic professionalism is often couched in terms of competing individual and societal values. Indeed, the welfare of individuals is often secondary to the requirements of society, especially given the public nature of courts of law, forensic hospitals, jails, and prisons. We explore the weaknesses of this dichotomous approach to forensic ethics, offering an analysis of Psychology's historical narrative especially relevant to the national security and correctional settings. We contend that a richer, more robust ethical analysis is available if practitioners consider the multiple perspectives in the forensic encounter, and acknowledge the multiple influences of personal, professional, and social values. The setting, context, or role is not sufficient to determine the ethics of forensic practice.
ContributorsCandilis, Philip J. (Author) / Neal, Tess M.S. (Author)
Created2013-12-28
Description
Burnout has become an increasingly popular topic among registered nurses, but unfortunately burnout among psychiatric nursing is less understood than other nursing specialties such as the Intensive Care Unit, Emergency Room, or Oncology. Psychiatry is unique and psychiatric nurses, in particular, are often subjected to physical and verbal violence as well as exposure to patient’s trauma. The aim of this project was to decrease burnout among psychiatric nurses in a private practice out-patient family psychiatric facility using Rossworm and Larabee’s change model (Appendix D). The MBI-HSS was completed by 1 participant (n=1) at pre-intervention and post-intervention. Between the pre/post MBI-HSS questionnaire the participant was asked to partake in a mindfulness-based intervention utilizing the smartphone application Headspace to complete a 10-session meditation course over one week. The results conclude the participant’s burnout decreased overall from pre-intervention to post-intervention. Internal Review Board (IRB) was granted in September 2021, and the project was completed in November 2021. The impact of the project was projected to have a more thorough statistical influence, but due to the participant size, there is minimal impact of system or polices in the psychiatric facility.
ContributorsSteward, M. Shannon (Author) / Guthrey, Ann (Thesis advisor) / Arizona State University. College of Nursing & Healthcare Innovation (Contributor)
Created2022-04-30