Matching Items (15)
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- All Subjects: Mental Health
- Creators: School of Social and Behavioral Sciences
- Status: Published
Description
Interest in health and wellness has significantly increased in today's society. Living a healthy and active lifestyle is suggested to promote overall physical and psychological well-being. This study explored the effects of wearing a Fitbit Zip activity monitor and the impact of expressing mindfulness on levels of physical activity. It was predicted that expressing mindfulness, as measured by the use of present-tense language during the daily emotional writing task, would moderate the relationship between wearing a Fitbit Zip activity monitor and change in physical activity. Specifically, it was hypothesized daily monitoring would only lead to increased activity among those higher in mindful language. Over the course of five days, participants were asked to wear a Fitbit Zip and to complete a daily questionnaire and writing task at the end of each evening. On the last day of the study, participants completed a follow-up assessment, which suggested that the combination of wearing a Fitbit Zip activity monitor and expressing more mindfulness throughout the week increased levels of physical activity. An important issue for future research is to conduct this study for a longer period of time in order to get more variability in the data. However, despite the limitations of the design, these findings suggest that activity monitoring may be a promising way to promote healthy lifestyle change.
ContributorsTarachiu, Viorela (Author) / Newman, Matt L. (Thesis advisor) / Hall, Deborah (Committee member) / Salerno, Jessica (Committee member) / Arizona State University (Publisher)
Created2014
Description
Bexarotene is a commercially produced drug commonly known as Targetin presecribed to treat cutaneous T-cell lymphoma (CTCL). Bex mimics the actions of natural 9-cis retinoic acid in the body, which are derived from Vitamin A in the diet and boost the immune system. Bex has been shown to be effective in the treatment of multiple types of cancer, including lung cancer. However, the disadvantages of using Bex include increased instances of hypothyroidism and excessive concentrations of blood triglycerides. If an analog of Bex can be developed which retains high affinity RXR binding similar to the 9-cis retinoic acid while exhibiting less interference for heterodimerization pathways, it would be of great clinical significance in improving the quality of life for patients with CTCL. This thesis will detail the biological profiling of additional novel (Generation Two) analogs, which are currently in submission for publication, as well as that of Generation Three analogs. The results from these studies reveal that specific alterations in the core structure of the Bex "parent" compound structure can have dramatic effects in modifying the biological activity of RXR agonists.
ContributorsYang, Joanna (Author) / Jurutka, Peter (Thesis director) / Wagner, Carl (Committee member) / Hibler, Elizabeth (Committee member) / Barrett, The Honors College (Contributor)
Created2012-05
Description
Bexarotene (Targretin®) is an FDA approved drug used to treat cutaneous T-cell lymphoma (CTCL), as well as off-label treatments for various cancers and neurodegenerative diseases. Previous research has indicated that bexarotene has a specific affinity for retinoid X receptors (RXR), which allows bexarotene to act as a ligand-activated-transcription factor and in return control cell differentiation and proliferation. Bexarotene targets RXR homodimerization to drive transcription of tumor suppressing genes; however, adverse reactions occur simultaneously when bound to other nuclear receptors. In this study, we used novel bexarotene analogs throughout 5 iterations synthesized in the laboratory of Dr. Wagner to test for their potency and ability to bind RXR. The aim of our study is to quantitatively measure RXR homodimerization driven by bexarotene analogs using a yeast two-hybrid system. Our results suggests there to be several compounds with higher protein activity than bexarotene, particularly in generations 3.0 and 5.0. This higher affinity for RXR homodimers may help scientists identify a compound that will minimize adverse effects and toxicity of bexarotene and serve as a better cancer treatment alternative.
ContributorsSeto, David Hua (Author) / Marshall, Pamela (Thesis director) / Wagner, Carl (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Natural Sciences (Contributor) / School of Social and Behavioral Sciences (Contributor)
Created2015-05
Description
The goal of this thesis was to create a resource addressing non-course-specific (NCS) student needs that College of Integrative Sciences and Arts (CISA) faculty can provide to their students when appropriate. Students attend faculty office hours for a variety of reasons, and not all are academic in nature. Data was collected in order to determine which resources were lacking in addressing these needs. Student need was identified through a 13-item survey regarding faculty perception of NCS student needs, including the primary reason for office hour visitation and the primary sources of stress, academic advising, and time management complaints from their students. Additionally, feedback was collected regarding faculty perception of available resources and likelihood of utilizing a new resource. Throughout the Downtown, Tempe, and Polytechnic campuses, 24 faculty responded. It was found that work stress, familial stress, academic advising requests, and students comments of being overwhelmed were the primary NCS student needs as perceived by faculty. Additionally, the majority of faculty reported not feeling fully equipped to address these needs. This information was used to create a resource compiling a list of University and off-campus tools that students can access to address these needs. The resource combined data from faculty and from the literature to address general and specific issues of stress, academic advising, feeling ‘off,’ and recovery and was created a double-sided handout to be used electronically or for print. It is currently available for faculty use. With further research, this resource could be expanded or refined to address the needs of a larger population of students in different colleges or on different campuses. Eventually, this could be used as a University-wide tool.
ContributorsMcAnally, Kaylyn Marie (Author) / Chisum, Jack (Thesis director) / Lisenbee, Cayle (Committee member) / School of Social and Behavioral Sciences (Contributor) / College of Health Solutions (Contributor) / Barrett, The Honors College (Contributor)
Created2019-05
Description
This research explores how to best communicate positive body images to women. This project was intended to improve a blog I created my freshmen year in college called You're Not A Potato where I used original illustrations to tell a narrative about body image issues. The thesis begins with an historical overview of body image issues and finds that women have been dealing with high levels of body dissatisfaction since the Victorian era. The thesis then recaps the role of traditional media as well as contemporary social media and the role they play in imposing rigid beauty ideals on women's bodies. After an analysis of social media culture, it becomes evident women still communicate about their bodies in a negative manner, not only towards themselves, but towards others. To address this issue, I define the Body Positive movement and explore how public figures are using social media to implement Body Positivity. To conclude this project, I utilize my new-found knowledge in body positive communication by impacting my university campus community. I started a "You're Not a Potato" Campaign for Body Pride week with the help of the ASU Wellness Team and designed and facilitated several engaging programs that reflected the values of the Body Positive movement to our students. Through this research, I discovered how our appearance-based culture has stolen self-confidence from young women today, but by the end of this project, I explain how we can attempt to rebuild our culture by effectively communicating self-love and body acceptance in our online and physical communities.
ContributorsMouton, Brianna Anais (Author) / Gruber, Diane (Thesis director) / Taylor, Jameien (Committee member) / Manninen, Bertha (Committee member) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Numerous studies have established that during the transition to parenthood couples experience changes within their relationship as well as in their overall mental health. The present study examines these changes specifically through conflict interactions. The author proposes the more conflict that occurs within a relationship, the lower each individual's self-esteem; the lowered self-esteem then leads to signs of depression. The present study's analysis consisted of two primary aims: 1) examine the association between romantic relationship conflict and mental health by using a proposed mediational pathway, in which self-esteem explains the connection, and 2) explore gender differences. The study aims were examined using secondary data analyses of Dr. Kristin Mickelson's study on couples transitioning to parenthood (Baby TIME Study). Results varied by conflict type as well as gender. When conflict was measured by perceived negative spousal interactions, results showed that the proposed mediational pathway was significant for men, but not for women. When conflict was measured by frequency of spousal arguments, results showed that the proposed mediational pathway was significant for women, but not for men. Furthermore, the results from this analysis indicate that during the transition to parenthood, men and women are affected by conflict differently in regards to their self-esteem and further their reported levels of depression.
ContributorsHoyt, Alyssa Aileen (Author) / Mickelson, Kristin (Thesis director) / Hall, Deborah (Committee member) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
Description
Trauma is increasingly experienced by people in transit as border militarization increases migrants’ exposure to violence and forces them into more precarious situations. For queer migrants, this includes situations where they are more likely to experience persecution and sexual violence. This paper explores the availability of care for queer undocumented migrants in the United States after surviving a precarious and potentially deadly journey from their country of origin to the US, as well as forms of alternative care developed by the undocuqueer community. In particular, it focuses on access to care for LGBT migrants, who face stigmatization on multiple levels and as a result are more likely than their straight counterparts to experience extreme mental health consequences pre-, in-, and post-transit. Faced with a number of obstacles that prevent them from receiving appropriate mental health care, the undocuqueer community utilizes various strategies to ensure that the health and needs of the community are supported. I argue that in spite of facing traumatic experiences and being unable to fully access healthcare to alleviate these problems in the US, LGBT migrants demonstrate extreme resilience and resist the mechanisms that otherwise threaten their mental well-being.
ContributorsCordwell, Cailan Rose (Author) / Wheatley, Abby C. (Thesis director) / Ward, Mako Fitts (Committee member) / School of Human Evolution & Social Change (Contributor) / Department of Psychology (Contributor) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description
The COVID-19 pandemic has affected many aspects of daily life due to social distancing guidelines, including physical exercise. Prior research indicates that physical activity is a potent resilience factor against stress’ impact on mental health. Further, research suggests that social integration and participation positively contributes to mental well-being. Yet, one aspect of physical activity that may be particularly impacted by social distancing guidelines is the social context. It is unclear if those who participated in social physical activity prior to the COVID pandemic are more impacted by the restrictions placed on these behaviors. In a sample of 519 adults in the United States, the current longitudinal study examined whether participation in social physical activity, compared to individual physical activity, moderates the influence of pandemic stress on mental health and whether there are gender differences between men and women in these associations. Study results indicated physical activity did benefit mental health during the COVID pandemic. However, greater social physical activity did not buffer against the negative impact of stress. Future research should examine other variables potentially influencing these relationships, and examine them under non-pandemic conditions.
ContributorsKaneris, Marianna Irene (Author) / Mickelson, Kristin (Thesis advisor) / Hall, Deborah (Committee member) / Mean, Lindsey (Committee member) / Arizona State University (Publisher)
Created2022
Description
Although adverse events cannot always be prevented, the negative outcomes on development can potentially be modified by considering methods of fostering positive emotional and behavioral responses. The study examined biopsychosocial health outcomes in the presence of uncontrollable adverse childhood events with the goal of identifying a potential intervention to increase resilience, health, and safe behaviors among at-risk children. It was hypothesized that adverse events can result in positive biopsychosocial outcomes in the presence of high scores on the Positive Emotion, Engagement, Relationships, Meaning, and Accomplishments (PERMA) model of well-being, self-efficacy, gratitude, and the ability to envision a positive future self. The study retrospectively examined adverse childhood events and present behavioral, emotional, and physical health outcomes. Participant (n = 685) data were analyzed using Hayes PROCESS (v3.5) to test all components of the moderation model. Results suggest that as adverse events increase, health adversity also increases. However, those with high intrapersonal strengths showed better health outcomes. Through understanding intrapersonal pathways in the presence of adverse events, the study can potentially identify mechanisms important for promoting resilient outcomes in childhood that could cascade into adulthood.
ContributorsBraunstein, Bailey Marie (Author) / Mickelson, Kristin (Thesis advisor) / Hall, Deborah (Committee member) / Lindstrom-Johnson, Sarah (Committee member) / Arizona State University (Publisher)
Created2022
Description
Transgender populations display disproportionately poorer health outcomes compared to the general population. On average, these populations tend to experience decreased well-being in part through increased mental health concerns (e.g., anxiety, depression) and poorer physical and behavioral health status. Understanding the process by which these deleterious outcomes occur for this population is integral to developing interventions. This thesis aimed to examine whether experiences of gender dysphoria and body dissatisfaction influenced the association of felt pressure to conform to gender norms with mental health and quality of life outcomes. Specifically, I hypothesized that greater pressure to conform to gender norms would be directly related to worse mental health and quality of life outcomes, and that gender dysphoria and body dissatisfaction would indirectly mediate this relationship. Furthermore, I hypothesized that participants' gender identity would moderate this relationship, such that transgender individuals would show stronger associations on all pathways as compared to cisgender individuals. The sample consisted of 211 individuals – 109 being transgender and 102 being cisgender. Participants completed a 15-minute online survey including a consent form. Results indicated partial support of hypotheses – pressure to conform to gender norms directly predicted outcomes of compromised mental health (i.e., depression, anxiety, and stress), but did not predict well-being or quality of life. Furthermore, gender dysphoria (but not body dissatisfaction) mediated the relationship between felt pressure for gender conformity and compromised mental health outcomes for cisgender participants, but unexpectedly not for transgender participants. Post hoc analyses suggest that perceived discrimination mediated the relation between felt pressure and all mental health measures and quality of life measures for both transgender and cisgender participants.
ContributorsKlennert, Victoria Elizabeth (Author) / Mickelson, Kristin (Thesis advisor) / Hall, Deborah (Committee member) / Nelson-Coffey, Katherine (Committee member) / Arizona State University (Publisher)
Created2023