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The current study investigated whether intermittent restraint stress (IRS) would impair fear extinction learning and lead to increased anxiety and depressive- like behaviors and then be attenuated when IRS ends and a post- stress rest period ensues for 6 weeks. Young adult, male Sprague Dawley rats underwent restraint stress using

The current study investigated whether intermittent restraint stress (IRS) would impair fear extinction learning and lead to increased anxiety and depressive- like behaviors and then be attenuated when IRS ends and a post- stress rest period ensues for 6 weeks. Young adult, male Sprague Dawley rats underwent restraint stress using wire mesh (6hr/daily) for five days with two days off before restraint resumed for three weeks for a total of 23 restraint days. The groups consisted of control (CON) with no restraint other than food and water restriction yoked to the restrained groups, stress immediate (STR-IMM), which were restrained then fear conditioned soon after the end of the IRS paradigm, and stress given a rest for 6 weeks before fear conditioning commenced (STR-R6). Rats were fear conditioned by pairing a 20 second tone with a footshock, then given extinction training for two days (15 tone only on each day). On the first day of extinction, all groups discriminated well on the first trial, but then as trials progressed, STR-R6 discriminated between tone and context less than did CON. On the second day of extinction, STR- IMM froze more to context in the earlier trials than compared to STR-R6 and CON. As trials progressed STR-IMM and STR-R6 froze more to context than compared to CON. Together, CON discriminated between tone and context better than did STR-IMM and STR-R6. Sucrose preference, novelty suppressed feeding, and elevated plus maze was performed after fear extinction was completed. No statistical differences were observed among groups for sucrose preference or novelty suppressed feeding. For the elevated plus maze, STR-IMM entered the open arms and the sum of both open and closed arms fewer than did STR- R6 and CON. We interpret the findings to suggest that the stress groups displayed increased hypervigilance and anxiety with STR-R6 exhibiting a unique phenotype than that of STR-IMM and CON.
ContributorsShah, Vrishti Bimal (Author) / Conrad, Cheryl (Thesis director) / Newbern, Jason (Committee member) / Judd, Jessica (Committee member) / School of Life Sciences (Contributor) / Sanford School of Social and Family Dynamics (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Monoamine neurotransmitters (e.g., serotonin, norepinephrine, and dopamine) are powerful modulators of mood and cognitive function in health and disease. We have been investigating the modulation of monoamine clearance in select brain regions via organic cation transporters (OCTs), a family of nonselective monoamine transporters. OCTs are thought to complement the actions

Monoamine neurotransmitters (e.g., serotonin, norepinephrine, and dopamine) are powerful modulators of mood and cognitive function in health and disease. We have been investigating the modulation of monoamine clearance in select brain regions via organic cation transporters (OCTs), a family of nonselective monoamine transporters. OCTs are thought to complement the actions of selective monoamine transporters in the brain by helping to clear monoamines from the extracellular space; thus, assisting to terminate the monoamine signal. Of particular interest, stress hormones (corticosterone; CORT) inhibit OCT3-mediated transport of monoamine, to putatively lead to prolonged monoamine signaling. It has been demonstrated that stress levels of CORT block OCT3 transport in the rat hypothalamus, an effect that likely underlies the rapid, stress-induced increase in local monoamines. We examined the effect of chronic variable stress (CVS) on the development of mood disorders and OCT3 expression in limbic and hypothalamic regions of the rat brain. Animals subjected to CVS (14-days with random stressor exposure two times/day) showed reduced body weight gain, indicating that CVS was perceived as stressful. However, behavioral tests of anxiety and depressive-like behaviors in rats showed no group differences. Although there were no behavioral effects of stress, molecular analysis revealed that there were stress-related changes in OCT3 protein expression. In situ hybridization data confirmed that OCT3 mRNA is expressed in the hippocampus, amygdala, and hypothalamus. Analysis of Western blot data by two-way ANOVA revealed a significant treatment effect on OCT3 protein levels, with a significant decrease in OCT3 protein in the amygdala and hippocampus in CVS rats, compared to controls. These data suggest an important role for CORT sensitive OCT3 in the reduction of monoamine clearance during stress.
ContributorsBoyll, Piper Savannah (Author) / Orchinik, Miles (Thesis director) / Conrad, Cheryl (Committee member) / Talboom, Joshua (Committee member) / School of Life Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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This Barrett, the Honors College senior thesis connects the experiences of cosplay with public speaking confidence. “Cosplay, abbreviated from the word ‘costume play,’ is a performance art in which the participant masquerades as a character from a selected film, television, video game, or comic book” (Gn, 2011, p. 583). The

This Barrett, the Honors College senior thesis connects the experiences of cosplay with public speaking confidence. “Cosplay, abbreviated from the word ‘costume play,’ is a performance art in which the participant masquerades as a character from a selected film, television, video game, or comic book” (Gn, 2011, p. 583). The ability to “cosplay” in front of other relies on performing in front of an audience much like public speaking. When students speak with confidence, students will know their ideas are being expressed with conviction and assurance. Having the ability to speak professionally and publicly, is a highly valued skill in the workforce and key to success in all types of employment. Communication skills are frequently a top factor in determining whether a college student will obtain employment (Beebe & Beebe, 2006, p. 275-276). Despite their different definitions, there are multiple connections between cosplay and public speaking. This thesis explores the connection between peer support and belief in one’s self in both cosplay and public speaking. Now those who have direct support become self-reliant and confident as a result of these connections. This projects highlights Goffman’s identity theory, the Pygmalion effect, theories of fashion and identity, role-play, narrative paradigm, dramatism, and non-verbal communication, and explores how cosplay can contribute to the formation of one’s public speaking persona. The issue of anxiety is also included in the conversation as it is central to both cosplay and public speaking. Ultimately, this thesis explores the questions: Can cosplay help students become empowered public speakers?
ContributorsGallardo Rojas, Lizette (Author) / Ramsey, Ramsey Eric (Thesis director) / Wentzel, Bonnie (Committee member) / School of Social and Behavioral Sciences (Contributor) / School of Criminology and Criminal Justice (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05
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It took the coming together of a community of people and their collective efforts to bring me where I am today academically. I would first like to thank Barrett, especially Dean Ramsey who helped build my appreciation for reading primary text, and NCUIRE for awarding me the grant for this

It took the coming together of a community of people and their collective efforts to bring me where I am today academically. I would first like to thank Barrett, especially Dean Ramsey who helped build my appreciation for reading primary text, and NCUIRE for awarding me the grant for this project. I want to extend my gratitude to Dr. Jeffery Kassing for being more than a director for my thesis by patiently listening to me talk about my future aspiration, and Dr. Jim Reed for being a mentor and a second reader. I would also like to thank all the multitude of professors and other mentors who helped shape my perspective in seeing the bigger picture. I am mostly grateful to all those who directly and indirectly helped bring this thesis to realization. Lastly, but certainly not the least, I would like to say a big thank you to my entire family, loved ones, and friends here and back home for enthusiastically cheering me on.
ContributorsWento, Christiana Tally (Author) / Kassing, Jeffrey (Thesis director) / Reed, James (Committee member) / Barrett, The Honors College (Contributor) / School of Social and Behavioral Sciences (Contributor)
Created2015-05
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This thesis aims to enhance the academic conception of American anti-Semitism by analyzing the rhetorical visions of two distinctly American theologies: Christian Identity and Black Israelism. Using a theoretical framework that couches the rhetoric of both religious movements within their respective historical contexts, I seek to understand the persuasive appeals

This thesis aims to enhance the academic conception of American anti-Semitism by analyzing the rhetorical visions of two distinctly American theologies: Christian Identity and Black Israelism. Using a theoretical framework that couches the rhetoric of both religious movements within their respective historical contexts, I seek to understand the persuasive appeals of the alternative histories that lead both movements to conclude that their racial group is descended from the ancient Israelites--a status both movements claim has been "usurped" by contemporary Jews. After contextualizing their rhetoric, I juxtapose the rhetorical vision of Christian Identity with that of Black Israelism, concluding that the former can be understood as a movement and narrative premised on racial hubris whose paranoid rhetoric makes meaningful contributions to the climate of anti-Semitism, while the latter constitutes a movement and narrative premised on historically-legitimated suspicion whose paranoid rhetoric, though invidious, does not constitute a comparable threat.
ContributorsRuben, Brian (Author) / Walker, Michael (Thesis director) / Mueller, Caroll (Committee member) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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The purpose of this thesis is to examine the relationship between mental illness and capitalist consumer society. Many Americans are suffering from mental illness and there has to be something causing it besides a chemical imbalance in the brain. A capitalist society creates a set of expectations that conflict with

The purpose of this thesis is to examine the relationship between mental illness and capitalist consumer society. Many Americans are suffering from mental illness and there has to be something causing it besides a chemical imbalance in the brain. A capitalist society creates a set of expectations that conflict with human desires. The thesis takes a historical, economical, and psychological approach to answering the following question: Does a capitalist society make its citizens mentally sick? A brief history of capitalism over the past century is discussed, as well as a more in depth look at capitalism and the creation of neoliberalism during the 1980s. The psychological effects capitalism has on human beings is discussed for the majority of the thesis and focuses on ideas from the 1950s as well as the early 2000s. To show the effect capitalism has on modern day society, an analysis of a psychopharmaceutical drug commercial is given. The concluding thoughts attempt to offer solutions to the problems of human unhappiness in a consumer culture.
ContributorsSerki, Aisling Erin (Author) / Gruber, Diane (Thesis director) / Ramsey, Ramsey Eric (Committee member) / Barrett, The Honors College (Contributor) / School of Social and Behavioral Sciences (Contributor)
Created2014-05
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This ethnographic study investigates the lives and identities of immigrant youth in Arizona. It explores their efforts to resolve their Mexican and American identities as shifting immigration policies threaten their immigration status. These youths are DACA (Deferred Action for Childhood Arrivals) recipients, former unauthorized migrants brought to the United States

This ethnographic study investigates the lives and identities of immigrant youth in Arizona. It explores their efforts to resolve their Mexican and American identities as shifting immigration policies threaten their immigration status. These youths are DACA (Deferred Action for Childhood Arrivals) recipients, former unauthorized migrants brought to the United States as children by their families and granted temporary lawful status and work authorization by the Obama administration in 2012. Arizona is home to nearly 26,000 DACA recipients. Through participant observation, and in-depth interviews (structured and unstructured), this study examines DACA recipients' distinctive and ambivalent integration as Americans. The author's own experience as a DACA recipient provides an insider's perspective, creating an auto-ethnographic exploration of identity that opens insights into the experiences of others. Narratives elicited from eleven DACAmented young adults provide an ethnographic lens through which to explore the complex concept of belonging, an often-contradictory attempt to find acceptance in American society while also embracing their cross-border cultural formation. Examination of their everyday experiences shows that the acknowledged privileges granted by the DACA program do effectively further enculturate DACA recipients into American society; yet capricious U.S. and Arizona immigration policies simultaneously contest the legitimacy of DACA recipients' decisive inclusion into the state and the nation. The coherence of their identities is thus destabilized, obligating them to adopt identities that are either fixed, conflictual, fluid, or new.
ContributorsHurtado Moreno, Argenis (Author) / Koptiuch, Kristin (Thesis director) / Kim, Linda (Committee member) / School of Sustainability (Contributor) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Alzheimer's disease and related dementias are a growing issue in the United States. While medical experts try to develop treatments or a cure, what are we as a society to do in the meantime to help those living with Alzheimer's? The arts seem to be an answer. In this thesis,

Alzheimer's disease and related dementias are a growing issue in the United States. While medical experts try to develop treatments or a cure, what are we as a society to do in the meantime to help those living with Alzheimer's? The arts seem to be an answer. In this thesis, I highlight numerous programs already in place across the United States that utilize the visual, musical, and dramatic arts to give people with Alzheimer's an avenue for expression, a connection to the world around them, as well as a better quality of life. I address the largely positive impact these arts engagement programs have on caregivers and their perceptions of their loved ones. I discuss what it means to have narrative identity and personhood in the midst of a disease that appears to strip those things away. Finally, I share my own experiences creatively engaging with residents at a local memory care facility and what those experiences demonstrated with regard to narrative, being, and Self. The examination of material and experiences demonstrates that art taps into innate parts of human beings that science is unable to touch or treat; however, the reverse is also true for science. When faced with an issue as complex as Alzheimer's disease, art and science are strongest together, and I believe the cure to Alzheimer's lies in this unity. In the meantime, we must utilize the arts to validate the Selves of and improve the quality of life for our growing Alzheimer's population.
ContributorsSpeight, Gemma (Author) / Gruber, Diane (Thesis director) / Manninen, Bertha (Committee member) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2018-05
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Depression is a prominent world disorder. Many prior studies have examined the biological, cognitive, and social elements of depression; however, few studies attempt to examine what role culture plays in this disorder. If culture plays such a large role in human development, it only makes sense that it would have

Depression is a prominent world disorder. Many prior studies have examined the biological, cognitive, and social elements of depression; however, few studies attempt to examine what role culture plays in this disorder. If culture plays such a large role in human development, it only makes sense that it would have an impact on a society's depression experience. Furthermore, conformity has been found to play a large role in the behaviors and mood states of adolescents. If conformity holds such control within this population, it is likely that said conformity could be adapted to any decided behavior. Although there has been research conducted on depression, culture, and conformity separately, these concepts are not often looked at in unison. For this reason, the current thesis focuses on the interaction between depression, culture, and conformity by defining depression-culture and depression-conformity, examining the manifestation of these concepts within American society, and analyzing the effects of these concepts.
ContributorsAnderson, Hayley Diane (Author) / Mickelson, Kristin (Thesis director) / Neal, Tess (Committee member) / Gandhi, Shefali (Committee member) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-12
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The relevance of depression in the clinical realm is well known, as it is one of the most common mental disorders in the United States. Clinical depression is the leading cause of disease for women worldwide. The sex difference in depression and anxiety has guided the research of not just

The relevance of depression in the clinical realm is well known, as it is one of the most common mental disorders in the United States. Clinical depression is the leading cause of disease for women worldwide. The sex difference in depression and anxiety has guided the research of not just recent studies but older studies as well, supporting the theory that gonadal hormones are associated with the mechanisms of emotional cognition. The scientific literature points towards a clear correlative relationship between gonadal hormones, especially estrogens, and emotion regulation. This thesis investigates the neural pathways that have been indicated to regulate mood and anxiety. Currently, the research points to the hypothalamic-pituitary-adrenal axis, which regulates the stress response through its ultimate secretion of cortisol through the adrenal cortex, and its modulated response when exposed to higher levels of estrogen. Another mechanism that has been investigated is the interaction of estrogen and the serotonergic system, which is noteworthy because the serotonergic system is known for its importance in mood regulation. However, it is important to note that the research seeking to determine the neurobiological underpinnings of estrogen and the serotonergic system is not expansive. Future research should focus on determining the direct relationship between cortisol hypersecretion and estrogens, the specific neurobiological effects of serotonergic receptor subtypes on the antidepressant actions of estrogens, and the simultaneous effects of the stress and serotonergic systems on depressive symptoms.

ContributorsArroyo, Mariana (Author) / Bimonte-Nelson, Heather (Thesis director) / Jurutka, Peter (Committee member) / School of International Letters and Cultures (Contributor) / School of Social and Behavioral Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05