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Description
Juvenile offenders suffer from substance use disorders at higher rates than adolescents in the general public. Substance use disorders also predict an increased risk for re-offending. Therefore, it is important that these juveniles, in particular, receive the appropriate substance use disorder treatment. The present study used logistic regression to test

Juvenile offenders suffer from substance use disorders at higher rates than adolescents in the general public. Substance use disorders also predict an increased risk for re-offending. Therefore, it is important that these juveniles, in particular, receive the appropriate substance use disorder treatment. The present study used logistic regression to test whether race/ethnicity would moderate the match between substance use disorder diagnosis and the receipt of a substance use disorder related service in a sample of male, serious juvenile offenders. Results showed that among those with a substance use disorder diagnosis, there were no race/ethnicity differences in the receipt of the appropriate service. However, among those without a substance use disorder diagnosis, non-Hispanic Caucasians were more likely to receive substance use service than were Hispanics or African-Americans. Post-hoc analyses revealed that when using a broader definition of substance use problems, significant differences by race/ethnicity in the prediction of service receipt were only observed at low levels of substance use problems. These findings shed light on how race/ethnicity may play a role in the recommendation of substance use disorder services in the juvenile justice system.
ContributorsMansion, Andre (Author) / Chassin, Laurie (Thesis advisor) / Dishion, Thomas (Committee member) / Knight, George (Committee member) / Arizona State University (Publisher)
Created2013
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Description
Levels of heavy episodic drinking peak during emerging adulthood and contribute to the experience of negative consequences. Previous research has identified a number of trait-like personality characteristics that are associated with drinking. Studies of the Acquired Preparedness Model have supported positive expectancies, and to a lesser extent negative expectancies, as

Levels of heavy episodic drinking peak during emerging adulthood and contribute to the experience of negative consequences. Previous research has identified a number of trait-like personality characteristics that are associated with drinking. Studies of the Acquired Preparedness Model have supported positive expectancies, and to a lesser extent negative expectancies, as mediators of the relation between trait-like characteristics and alcohol outcomes. However, expectancies measured via self-report may reflect differences in learned expectancies in spite of similar alcohol-related responses, or they may reflect true individual differences in subjective responses to alcohol. The current study addressed this gap in the literature by assessing the relative roles of expectancies and subjective response as mediators within the APM in a sample of 236 emerging adults (74.7% male) participating in a placebo-controlled alcohol challenge study. The study tested four mediation models collapsed across beverage condition as well as eight separate mediation models with four models (2 beverage by 2 expectancy/subjective response) for each outcome (alcohol use and alcohol-related problems). Consistent with previous studies, SS was positively associated with alcohol outcomes in models collapsed across beverage condition. SS was also associated with positive subjective response in collapsed models and in the alcohol models. The hypothesized negative relation between SS and sedation was not significant. In contrast to previous studies, neither stimulation nor sedation predicted either weekly drinking or alcohol-related problems. While stimulation and alcohol use appeared to have a positive and significant association, this relation did not hold when controlling for SS, suggesting that SS and stimulation account for shared variability in drinking behavior. Failure to find this association in the placebo group suggests that, while explicit positive expectancies are related to alcohol use after controlling for levels of sensation seeking, implicit expectancies (at least as assessed by a placebo manipulation) are not. That the relation between SS and stimulation held only in the alcohol condition in analyses separate by beverage condition indicates that sensation seeking is a significant predictor of positive subjective response to alcohol (stimulation), potentially above and beyond expectancies.
ContributorsScott, Caitlin (Author) / Corbin, William (Thesis advisor) / Shiota, Michelle (Committee member) / Chassin, Laurie (Committee member) / Arizona State University (Publisher)
Created2012
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Description
The hypothalamus pituitary adrenal (HPA) axis and the human genome are important components of the biological etiology of externalizing disorders. By studying the associations between specific genetic variants, diurnal cortisol, and externalizing symptoms we can begin to unpack this complex etiology. It was hypothesized that genetic variants from the corticotropine

The hypothalamus pituitary adrenal (HPA) axis and the human genome are important components of the biological etiology of externalizing disorders. By studying the associations between specific genetic variants, diurnal cortisol, and externalizing symptoms we can begin to unpack this complex etiology. It was hypothesized that genetic variants from the corticotropine releasing hormone receptor 1 (CRHR1), FK506 binding protein 51 (FKBP5), catechol-O-methyl transferase (COMT), and dopamine transporter (DAT1) genes and diurnal cortisol intercepts and slopes would separately predict externalizing symptoms. It was also hypothesized that genetic variants would moderate the association between cortisol and externalizing. Participants were 800 twins (51% boys), 88.5% Caucasian, M=7.93 years (SD=0.87) participating in the Wisconsin Twin Project. Hierarchical Linear Modeling (HLM) was used to separate the variance associated with state and trait cortisol measured across three consecutive days and trait cortisol measures were used. There were no main effects of genes on externalizing symptoms. The evening cortisol intercept, the morning cortisol slope and the evening cortisol slope predicted externalizing, but only in boys, such that boys with higher cortisol and flatter slopes across the day also had more externalizing symptoms. The morning cortisol intercept and CRHR1 rs242924 interacted to predict externalizing in both boys and girls, with GG carriers significantly higher compared to TT carriers at one standard deviation below the mean of morning cortisol. For boys only there was a significant interaction between the DAT1 variable number tandem repeat (VNTR) and the afternoon slope and a significant slope for 9/9 carriers and 9/10 carriers such that when the slope was more steep, boys carrying a nine had fewer externalizing symptoms but when the slope was less steep, they had more. Results confirm a link between diurnal trait cortisol and externalizing in boys, as well as moderation of that association by genetic polymorphisms. This is the first study to empirically examine this association and should encourage further research on the biological etiology of externalizing disorder symptoms.
ContributorsSwann, Gregory (Author) / Lemery-Chalfant, Kathryn (Thesis advisor) / Chassin, Laurie (Committee member) / Doane-Sampey, Leah (Committee member) / Arizona State University (Publisher)
Created2012
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Description
Although research has documented robust prospective relationships between externalizing symptomatology and subsequent binge drinking among adolescents, the extent to which internalizing symptoms increase risk for drinking remains controversial. In particular, the role of anxiety as a predictor of binge drinking remains unclear. Recent evidence suggests that one possible reason for

Although research has documented robust prospective relationships between externalizing symptomatology and subsequent binge drinking among adolescents, the extent to which internalizing symptoms increase risk for drinking remains controversial. In particular, the role of anxiety as a predictor of binge drinking remains unclear. Recent evidence suggests that one possible reason for these mixed findings is that separate dimensions of anxiety may differentially confer risk for alcohol use. The present study tested two dimensions of anxiety - worry and physiological anxiety -- as predictors of binge drinking in a longitudinal study of juvenile delinquents. Overall, results indicate that worry and physiological anxiety showed differential relations with drinking behavior. In general, worry was protective against alcohol use, whereas physiological anxiety conferred risk for binge drinking, but both effects were conditional on levels of offending. Implications for future research examining the role of anxiety in predicting drinking behavior among youth are discussed.
ContributorsNichter, Brandon (Author) / Chassin, Laurie (Thesis advisor) / Barrera, Manuel (Committee member) / Presson, Clark (Committee member) / Arizona State University (Publisher)
Created2014
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Description
The present study tested the factor structure of the externalizing disorders (e.g. attention-deficit hyperactivity disorder (ADHD), conduct disorder (SE), and substance experimentation (SE) ) in adolescence. In addition, this study tested the influence of the GABRA2 gene on the factors of the externalizing spectrum. Confirmatory factor analyses were used to

The present study tested the factor structure of the externalizing disorders (e.g. attention-deficit hyperactivity disorder (ADHD), conduct disorder (SE), and substance experimentation (SE) ) in adolescence. In addition, this study tested the influence of the GABRA2 gene on the factors of the externalizing spectrum. Confirmatory factor analyses were used to test the factor structure of the externalizing spectrum. Specifically, three competing alternate confirmatory factor analytic models were tested: a one-factor model where all disorders loaded onto a single externalizing factor, a two-factor model where CD and SE loaded onto one factor and ADHD loaded onto another, and a three-factor model, where all three disorders loaded onto separate factors. Structural equation modeling was used to test the effect of a GABRA2 SNP, rs279858, on the factors of the externalizing spectrum. Analyses revealed that a three-factor model of externalizing disorders with correlated factors fit the data best. Additionally, GABRA2 had a significant effect on the SE factor in adolescence, but not on the CD or ADHD factors. These findings demonstrate that the externalizing disorders in adolescence share commonalities but also have separate sources of systematic variance. Furthermore, biological mechanisms may act as a unique etiological factor in the development of adolescent substance experimentation.
ContributorsWang, Frances L (Author) / Chassin, Laurie (Thesis advisor) / Lemery-Chalfant, Kathryn (Committee member) / Geiser, Christian (Committee member) / Arizona State University (Publisher)
Created2012
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Description
The beginning of college is a period in which increased alcohol use often coincides with greater involvement in romantic relationships. Existing literature yields inconsistent findings regarding the influence of different relationship statuses on drinking behavior, perhaps because these studies have not accounted for recent changes in the way college students

The beginning of college is a period in which increased alcohol use often coincides with greater involvement in romantic relationships. Existing literature yields inconsistent findings regarding the influence of different relationship statuses on drinking behavior, perhaps because these studies have not accounted for recent changes in the way college students engage in dating/sexual relationships. In the current college environment, many students who define themselves as non-daters are nonetheless sexually active, a phenomenon referred to as the 'hook up' culture. The present study sought to address this issue by examining the effects of both relationship status and sexual activity on heavy episodic drinking (HED) among 1,467 college students over the course of their first three semesters. Results indicated that the effects of relationship status depended on whether or not an individual was sexually active. Non-dating but sexually active students reported rates of heavy drinking comparable to students who defined themselves as casual daters, but non-dating students who were not sexually active reported drinking behavior similar to those involved in committed relationships. Further, transitions between low and high risk relationship/sexual activity statuses were associated with corresponding changes in HED. Transitioning into a high risk status was associated with greater levels of heavy episodic drinking, whereas transitioning into a low risk status was associated with decreases in this behavior. Together, results indicate that engaging in nonexclusive dating or sexual relationships may play an important role in the development of problematic patterns of alcohol use during the early college years. These findings have potentially important implications both for future research and for prevention and intervention efforts targeting high risk college drinkers.
ContributorsZalewski, Suzanne (Author) / Corbin, Willaim (Thesis advisor) / Doane, Leah (Committee member) / Chassin, Laurie (Committee member) / Arizona State University (Publisher)
Created2012
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Description
Ethnic enclaves, or neighborhoods with high ethnic densities, have been linked with positive health outcomes and lower crime rates. Using data from the Pathways to Desistance project, this study tested whether neighborhood Latino concentration prospectively predicted re-offense rates among a sample of Mexican American juvenile offenders (n = 247). Further,

Ethnic enclaves, or neighborhoods with high ethnic densities, have been linked with positive health outcomes and lower crime rates. Using data from the Pathways to Desistance project, this study tested whether neighborhood Latino concentration prospectively predicted re-offense rates among a sample of Mexican American juvenile offenders (n = 247). Further, I tested whether the effect of neighborhood Latino concentration on re-offense was moderated by ethnic identity, Mexican orientation, and generation status. Covariates included demographics and risk factors for offending. Results showed that neighborhood Latino concentration, ethnic identity, Mexican orientation, and generation status were not predictive of re-offense rates. Gender, risk for offending, and time spent supervised during the follow-up period predicted re-offense rates one year later. The results highlight the importance of risk assessment for this high risk group.
ContributorsBui, Leena (Author) / Chassin, Laurie (Thesis advisor) / Knight, George (Committee member) / Tein, Jenn-Yun (Committee member) / White, Rebecca (Committee member) / Arizona State University (Publisher)
Created2018
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Description
The tendency for psychopathology to aggregate within families is well-documented, though little is known regarding the level of specificity at which familial transmission of symptomology occurs. The current study first tested competing higher-order structures of psychopathology in adolescence, indexing general and more specific latent factors. Second, parent-offspring transmission was tested

The tendency for psychopathology to aggregate within families is well-documented, though little is known regarding the level of specificity at which familial transmission of symptomology occurs. The current study first tested competing higher-order structures of psychopathology in adolescence, indexing general and more specific latent factors. Second, parent-offspring transmission was tested for broadband domain specificity versus transmission of a general liability for psychopathology. Lastly, genetic and environmental mechanisms underlying the familial aggregation of psychopathology were examined using nuclear twin-family models. The sample was comprised of five hundred adolescent twin pairs (mean age 13.24 years) and their parents drawn from the Wisconsin Twin Project. Twins and parents completed independent diagnostic interviews. For aim 1, correlated factors, bifactor, and general-factor models were tested using adolescent symptom count data. For aim 2, structural equation modeling was used to determine whether broadband domain-specific transmission effects were necessary to capture parent-offspring resemblance in psychopathology above and beyond a general transmission effect indexed by the latent correlation between a parental internalizing factor and offspring P-factor. For aim 3, general factor models were fitted in both generations, and factor scores were subsequently extracted and used in nuclear twin-family model testing. Results indicated that the bifactor model exhibited the best fit to the adolescent data. Familial aggregation of psychopathology was sufficiently accounted for by the transmission of a general liability. Lastly, the best fitting reduced nuclear twin-family model indicated that additive genetic, sibling-specific shared environmental, and nonshared environmental influences contributed to general psychopathology. Parent-offspring transmission was accounted for by shared genetics only, whereas co-twin aggregation was additionally explained by sibling-specific shared environmental factors. Results provide novel insight into the specificity and etiology of the familial aggregation of psychopathology.
ContributorsOro, Veronica (Author) / Lemery-Chalfant, Kathryn (Thesis advisor) / Chassin, Laurie (Committee member) / Doane, Leah D (Committee member) / Arizona State University (Publisher)
Created2019
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Description
The present study aimed to test the effect of role socialization processes on declines in drinking after marriage. Role socialization as it relates to marriage theorizes that after occupying a role, individuals are likely to change their behaviors to conform to role expectations of marriage, such as reductions in drinking

The present study aimed to test the effect of role socialization processes on declines in drinking after marriage. Role socialization as it relates to marriage theorizes that after occupying a role, individuals are likely to change their behaviors to conform to role expectations of marriage, such as reductions in drinking (Yamaguchi & Kandel, 1985). Previous literature has examined declines in drinking behaviors after marriage and inferred that role socialization was the underlying process. This study is the first to directly test whether beliefs that alcohol is harmful to the marital role predicted declines in frequency of drunkenness after marriage. Ordered probit regression was used to test the effect of marriage-related motives to limit drinking on declines in frequency of drunkenness from before marriage to after marriage. Analyses revealed that marriage-related motives to limit drinking were not significantly predictive of declines in frequency of drunkenness after marriage. Only partner drinking emerged as a significant predictor of declines in frequency of drunkenness after marriage. These results highlight the need for a reliable and valid measure of role socialization processes as they relate to the marital role. Furthermore, future studies should consider studying participants at different time points after marriage and consider measuring commitment to the marital role as a moderator. Such studies will help to better understand the results of this study as well as better understand the marriage effect on drinking.
ContributorsSternberg, Ariel (Author) / Chassin, Laurie (Thesis advisor) / Grimm, Kevin (Committee member) / Corbin, Will (Committee member) / Arizona State University (Publisher)
Created2016
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Description
There is a growing trend among community samples of young, adult women to initiate drug use for weight loss (Boys, Marsden, & Strang, 2001; Mendieta-Tan, Hulbert-Williams, & Nicholls, 2013). Research has suggested that consequential weight loss may maintain drug use (Cohen, et al., 2010; Ersche, Stochl, Woodward, & Fletcher, 2013;

There is a growing trend among community samples of young, adult women to initiate drug use for weight loss (Boys, Marsden, & Strang, 2001; Mendieta-Tan, Hulbert-Williams, & Nicholls, 2013). Research has suggested that consequential weight loss may maintain drug use (Cohen, et al., 2010; Ersche, Stochl, Woodward, & Fletcher, 2013; Sirles, 2002), which is compounded by women's perception that drugs are convenient and guarantee weight loss (Mendieta-Tan, et al., 2013). Stimulants, including cocaine, amphetamine, methamphetamine, and ecstasy, are notable drugs of use among college students (Johnston, et al., 2014; Teter, McCabe, LaGrange, Cranford, & Boyd, 2006). With known appetitive and metabolic effects, stimulants may be particularly attractive to college women, who are at elevated risk for increased body dissatisfaction and experimenting with extreme weight loss techniques (Grunewald, 1985; National Eating Disorder Association, 2013). A preliminary epidemiological study of 130 college women between 16- and 24-years old (Mage = 18.76, SDage = 1.09) was conducted to begin to investigate this phenomenon. Results showed women who reported use for weight control (n = 19, 14.6 %) predominantly used stimulants (68.4%), and this subgroup was severely elevated on global and subscales of eating pathology compared with college norms. Moreover, the odds of stimulant use were doubled when women engaged in a compensatory behavior, such as excessive exercise, self-induced vomiting, and laxative use. Although preliminary, these results suggest that a desire for weight control may be associated with stimulant use among college women. Women engaging in more extreme weight loss behaviors are at high risk for initiating and maintaining illicit stimulant use for weight-related reasons.
ContributorsBruening, Amanda B (Author) / Perez, Marisol (Thesis advisor) / Grimm, Kevin (Committee member) / Chassin, Laurie (Committee member) / Arizona State University (Publisher)
Created2016