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- All Subjects: psychology
- Genre: Doctoral Dissertation
- Creators: Corbin, William
- Status: Published
Description
Anxiety disorder diagnosis is a risk factor for alcohol use disorders (AUDs), but mechanisms of risk are not well understood. Studies show that anxious individuals receive greater negative reinforcement from alcohol when consumed prior to a stressor, but few studies have examined whether anxious individuals receive greater negative (or positive) reinforcement from alcohol in a general drinking context (i.e., no imminent stressor). Previous studies have also failed to examine possible moderating effects of specific drinking contexts (e.g., drinking in a group or alone). Finally, no studies have investigated mediating variables that might explain the relationship between anxiety and reinforcement from alcohol, such as physiological response to alcohol (e.g., cortisol response). Data for this study were drawn from a large alcohol administration study (N = 447) wherein participants were randomized to receive alcohol (target peak BAC: .08 g%) or placebo in one of four contexts: group simulated bar, solitary simulated bar, group sterile laboratory, solitary sterile laboratory. It was hypothesized that anxiety would be associated with positive subjective response (SR) under alcohol (above and beyond placebo), indicating stronger reinforcement from alcohol. It was also hypothesized that social and physical drinking context would moderate this relationship. Finally, it was hypothesized that anxiety would be associated with a blunted cortisol response to alcohol (compared to placebo) and this blunted cortisol response would be associated with stronger positive SR and weaker negative SR. Results showed that anxiety was not associated with positive SR in the full sample, but drinking context did moderate the anxiety/SR relationship in most cases (e.g., anxiety was significantly associated with positive SR (stimulation) under placebo in solitary contexts only). There was no evidence that cortisol response to alcohol mediated the relationship between anxiety and SR. This study provides evidence that anxious drinkers expect stronger positive reinforcement from alcohol in solitary contexts, which has implications for intervention (e.g., modification of existing interventions like expectancy challenge). Null findings regarding cortisol response suggest alcohol’s effect on cortisol response to stress (rather than cortisol response to alcohol consumption) may be more relevant for SR and drinking behavior among anxious individuals.
ContributorsMenary, Kyle Robert (Author) / Corbin, William (Thesis advisor) / Chassin, Laurie (Committee member) / Meier, Madeline (Committee member) / Grimm, Kevin (Committee member) / Arizona State University (Publisher)
Created2018
Description
Introduction: Edibles, THC-infused food products, are a popular type of cannabis. However, there is limited research on how acute effects of edibles differ from more traditional cannabis types, such as smoked flower (e.g., dried bud). The current study examined the subjective response of cannabis between smoked flower and edibles using a two-week long ecological momentary assessment (EMA). Sex differences were also examined.Method: Individuals (n=101) using both edibles and flower at least once weekly completed a cannabis report within 30 minutes (T1) of first cannabis use each day as well as two follow-up reports sent 1.5 (T2) and 3 hours (T3) after initial use. Participants additionally completed assessments throughout the day for fourteen consecutive days to examine daily affect. Multi-level models examined whether overall high, low-arousal negative effects, high-arousal negative effects, and general positive effects differed by edibles and flower. Given time differences in effects between cannabis types, subjective effects were examined at T1, T2, and T3, as well as for the peak effects across the three-hour time window. Covariates included demographics, variant- and invariant- cannabis use characteristics, and daily affect.
Results: At T1, edibles produced lesser positive effects (b=-0.60, S.E.=0.16, p=0.001) and overall high (b=-2.00, S.E.=0.27, p<0.001) relative to flower. At T2, edibles produced greater positive effects (b=0.52, S.E.=0.21, p=0.01) relative to flower. At T3, edibles produced greater low-arousal negative effects (b=0.63, S.E.=0.23, p=0.01) relative to flower. Edibles produced greater peak low-arousal effects relative to flower (b=0.59, S.E.=0.21, p=0.01), With respect to sex differences, there was an interaction between sex and cannabis type at T1 for positive effects (b=-0.99, S.E.=0.31, p=0.001), such that males reported greater positive effects for flower. Males additionally reported lesser low-arousal effects at T1 (b=-0.60, S.E.=0.30, p=0.05) and greater overall high at T3 relative to females (b=1.24, S.E.=0.56, p=0.03).
Discussion: Smoked flower produced greater effects immediately and edibles produced greater delayed effects. Edibles appear to have greater peak levels of low-arousal effects (e.g., sluggish, drowsy, slow) relative to smoked flower. Males may be more sensitive to the rewarding effects of cannabis, particularly when smoking flower.
ContributorsOkey, Sarah (Author) / Corbin, William (Thesis advisor) / Doane, Leah (Committee member) / Cruz, Rick (Committee member) / McNeish, Daniel (Committee member) / Arizona State University (Publisher)
Created2023
Description
Using data from a randomized, experimental trial of a brief family-based preventive intervention for parentally-bereaved families, this study evaluated whether participation in the Family Bereavement Program (FBP) when the offspring were in childhood/adolescence (ages 8 to 16) improved competencies when the offspring were emerging/young adults (ages 23 to 32). Participants were 244 emerging/young adults; data used were from assessments at pretest, posttest, 6 years post-intervention, and 15 years post-intervention. In addition to testing the direct effects of the program, developmental cascade effects models were used to test the relations between program-induced improvements in positive parenting and decreased negative life events at posttest and subsequent effects on domains of competence and behavior problems in adolescence/emerging adulthood (ages 14 to 22) and four developmental competencies of emerging/young adulthood: academic, peer, romantic, and work competence. Results supported a cascading effects model of program effects on competence outcomes. In the full sample, there were significant mediation effects of the intervention to decreased negative life events at posttest to increased grade-point average (GPA) at the 6-year follow-up to higher academic and work competence at the 15-year follow-up. For females only, two additional significant mediational pathways of the FBP occurred. The FBP led to an increase in peer competence 6 years post-intervention, which was associated with an increase in work competence 15 years post-intervention. Also, the FBP led to a decrease in externalizing problems in adolescence/emerging adulthood, but externalizing problems were positively associated with work competence. For males, additional mediation effects of the FBP on work competence occurred. The FBP decreased negative life events. However, higher negative life events were associated with lower externalizing problems in adolescence/emerging adulthood, and externalizing problems were positively associated with work competence. For males only, a significant three-pathway mediation effect of the intervention occurred on increased positive parenting at posttest to increased romantic attachment at the 6-year follow-up to higher romantic competence at the 15-year follow-up. Peer competence showed continuity over development. Mediational analyses highlighted the role of program-induced improvements in parenting, reductions in exposure to negative life events, and earlier developmental competencies on competence outcomes in emerging/young adulthood. Implications for promoting resilience in parentally-bereaved, at-risk youth are discussed.
ContributorsINGRAM, ALEXANDRA M (Author) / Wolchik, Sharlene (Thesis advisor) / Corbin, William (Committee member) / Infurna, Frank (Committee member) / Tein, Jenn-Yun (Committee member) / Arizona State University (Publisher)
Created2020
Description
Alcohol use among romantic partners is known to be related to a variety of detrimental outcomes, such as decreased relationship satisfaction and increases in conflict. However, discrepant drinking among partners may be a stronger predictor of relationship outcomes over and above the amount of alcohol use. Currently, little is known about potential differences in the within- and between-person effects and discrepancy’s effect on mood, particularly among community samples. The current study investigated the effects of both individual and partner alcohol use, as well as discrepant drinking, on mood and relationship functioning. Data were obtained from 280 heterosexual romantic couples using a measurement burst daily dairy design over the course of one year. Actor Partner Interdependence Model and Dyadic Score Model analyses were used to investigate the effect of alcohol use and discrepant drinking on mood and relationship functioning, both at the within- and between- person levels. Specifically, analyses investigated the effects of no drinking versus moderate drinking, no drinking versus binge drinking, and moderate drinking versus binge drinking. Results revealed that while binge drinking may be related to positive outcomes proximally, the cumulative effects at the between-person level are detrimental. Moreover, discrepant drinking appears most detrimental when women outdrink their partners. These findings have important implications for refining and improving upon couples-based interventions aimed at alcohol-use problems among non-clinical couples.
ContributorsChampion, Charlie (Author) / Corbin, William (Thesis advisor) / Ha, Thao (Committee member) / Iida, Masumi (Committee member) / Randall, Ashley (Committee member) / Arizona State University (Publisher)
Created2020
Description
Alcohol use disorder (AUD) causes immense global burden and has a significant impact on economic and societal functioning. Efficacious treatments for AUDs have been well-established within the literature, however the most commonly accessed treatments for AUD are alcohol-related services, such as self-help groups, outpatient clinics, and detoxification centers. Though studies suggest these services are effective at treating AUDs, there are numerous differences between individuals who receive alcohol-related services and individuals who do not, causing selection bias. Furthermore, current studies of alcohol-related services frequently define recovery outcomes as abstinence, which reduces variability in viable recovery outcomes, such as reduction of drinking behaviors. In addition, reduction in drinking and alcohol-related problems should theoretically have an impact on broader aspects of functioning, such as familial functioning. Improved familial context may reduce risk to family members, who are otherwise at heightened risk for emotional and behavioral problems when living with a family member with AUD. The current study investigated the effect of alcohol-related services on binary and continuous drinking outcomes after eliminating selection bias using multiple propensity score approaches, to identify the best methodology for a high-risk community sample of individuals with AUD. Propensity scores were created using logistic regression approaches and boosted regression trees. Matching, weighting, and subclassification were used, and matching was performed both using greedy and global approaches. Results suggested subclassification was the most successful method for real world alcohol-related services samples with moderate sample size. Moreover, findings demonstrated that boosted regression approaches were less successful than logistic regression approaches at minimizing the effects of selection bias on known confounding variables that are highly related to group selection. In addition, after removing the effects of selection bias, there were no significant difference between participants who received alcohol-related services and the comparison control group on drinking or family functioning, though both groups reduced drinking from pre- to post-alcohol-related services receipt. Findings suggest careful selection of quasi-experimental methods is warranted in real-world samples, to ensure optimal removal of selection bias. Moreover, future studies should continue to clarify the profile of individual that benefits from alcohol-related services to inform intervention efforts.
ContributorsSternberg, Ariel (Author) / Chassin, Laurie (Thesis advisor) / Corbin, William (Committee member) / Meier, Madeline (Committee member) / Grimm, Kevin (Committee member) / Arizona State University (Publisher)
Created2021
Description
Despite the established co-prevalence of substance use (SU) and disordered eating (DE), few longitudinal studies have sought to examine their shared development. Findings have been inconsistent within the extant literature. This may be attributable in part to several methodological aspects, including overlooking distinct psychopharmacological properties of common substances of abuse, examining only between-person relations, and failing to account for shared risk factors. The current study sought to address these gaps by applying latent curve models with structured residuals (LCM-SR) to a preexisting, national sample of adolescent girls followed into adulthood, Add Health. In Aim 1, between-person effects examined the simultaneous development of alcohol, tobacco, and marijuana use and DE behaviors in substance-specific models. In Aim 2, bivariate latent curve models were expanded to account for within-person effects (LCM-SR) in order to examine the potentially bidirectional, prospective relationship between use of a specific substance and DE. Lastly, models accounted for shared developmental risk factors. Findings of the current study demonstrate preliminary evidence of substance-specific effects with DE emerging in adolescence. Across model-building steps, DE engagement in early adolescence was significantly associated with growth in tobacco use and marginally associated with marijuana use. Appetitive side-effects of both substances may link use with DE behaviors and enhance instrumental use for weight control. Significant associations did not emerge between alcohol and DE, and results of the conditional model indicate this co-occurrence is best explained by third variable mechanisms. Implications for prevention are discussed.
ContributorsBruening, Amanda B (Author) / Corbin, William (Thesis advisor) / Chassin, Laurie (Committee member) / Meier, Madeline (Committee member) / McNeish, Daniel (Committee member) / Arizona State University (Publisher)
Created2021