Matching Items (67)

132639-Thumbnail Image.png

Black Widows on an Urban Heat Island: Understanding Physiological Responses to Global Change

Description

The steroid hormone 20-hydroxyecdysone (20E) controls molting in arthropods. The timing of 20E production, and subsequent developmental transitions, is regulated by a variety of factors including nutrition and photoperiod. Environmental

The steroid hormone 20-hydroxyecdysone (20E) controls molting in arthropods. The timing of 20E production, and subsequent developmental transitions, is regulated by a variety of factors including nutrition and photoperiod. Environmental factors, such as temperature, play a critical role in regulation as well. The increasing prevalence of urban heat islands (UHI), or areas with elevated temperature due to retained heat by built structures, in response to rapid urbanization has made it critical to understand how organisms respond to elevating global temperatures. Some arthropods, such as the Western black widow spider, Latrodectus hesperus, appear to thrive under UHI conditions, but the physiological mechanism underlying their success has not been explored. Recently, we have shown that L. hesperus, a troublesome urban pest, in fact responds to urban heat island conditions in Phoenix, AZ with delayed development, reduced body mass, and increased mortality. Here we look at the relationship between 20E levels and development in spiderlings reared under desert (27ᵒC), intermediate (30ᵒC), and urban (33ᵒC) temperatures, filling a noticeable gap in not only understanding ecdysteroids’ role in arachnid development but how incremental changes in environmental conditions affect the regulation of this process. Developmental progression and hemolymph 20E titers were recorded for several families of spiders collected from across the urban Phoenix area with data spanning from day 55 to 75 of development, focusing on the second developmental instar. We found that 33°C, but not 30°C, led to 1) a significantly higher production of 20E throughout development, 2) a reduced and delayed molt-inducing 20E peak, and 3) noticeable reductions in growth rate and mass. At 30°C, a variable response is seen in molt timing, without the negative impacts on size and mortality as seen at 33°C, suggesting that at UHI temperatures, the optimal developmental temperature threshold has been surpassed.

Contributors

Created

Date Created
  • 2019-05

132341-Thumbnail Image.png

Mobile App Development: The Use of Apache Cordova to Construct Features for iOS and Android Applications

Description

Mobile app development has been the fastest growing software development since the release of the iPhone in 2007 and the creation of the App Store in 2008. After the rise

Mobile app development has been the fastest growing software development since the release of the iPhone in 2007 and the creation of the App Store in 2008. After the rise in popularity of the smartphone and mobile app development, businesses started to shift from browser-based software to mobile platforms. There are multiple reasons that any company would want to reach out in the mobile environment, including attracting new customers, creating a better experience, expanding their brand, being more accessible, and overall growth. Developers started to build new platforms that would make it easy for not only their own company but anyone else to develop new applications at a faster pace. Today there are three different ways to create a mobile application: a native app, a hybrid app, and a web app. At DriveTime, we spent time researching and developing possible options for how we could make a mobile application to expand our user involvement. Our conclusion was to use a hybrid application that would incorporate our already existing web app and relaunch it as a native app. I took over this project for DriveTime and planned to implement two new features for their mobile application. Using Apache Cordova, I dived into the Software Development Life Cycle to create and deploy a Rate and Review feature and Push Notification functionality. In the end, I was only able to implement the Rate and Review feature due to some unexpected delays in development. I assumed all roles of a standard Agile development team to understand all of the different aspects that go into planning, creating, and publishing software.

Contributors

Agent

Created

Date Created
  • 2019-05

134503-Thumbnail Image.png

Associative Recognition of Odor Stimuli Variance and a Proposal to Test This in Odor Experience Restricted Honey Bees

Description

Recent data suggests that olfactory input is important for antennal lobe development in honey bees. Chronic association of a single odor to food resources during crucial stages of development results

Recent data suggests that olfactory input is important for antennal lobe development in honey bees. Chronic association of a single odor to food resources during crucial stages of development results in delayed antennal lobe development for mature foraging bees. The antennal lobes of these bees instead closely resemble an immature network observed in young, newly emerged bees. Using an odor stimuli variance assay, learning and memory tests can be used to explore how well honey bees discriminate single odors within complex odor mixtures. Here we are validating two different odor mixtures, a Brassica rapa floral blend and a second replicate mixture composed of common molecularly dissimilar odors. Odors in each mixture are either held constant or varied in concentration over 16 conditioning trials. Subsequent memory tests are performed two hours later to observe the ability of bees to distinguish and recognize specific odor components in each mixture. So far in our assay we find high rates of generalization for both odor mixtures. In general, more bees responded to all odors in the replicate treatment group over the Brassica treatment group. Additionally, bees in the Brassica treatment group did not respond to the target odor. More data is being collected to validate this assay. In future studies, I propose to apply this behavioral assay to bees with an altered olfactory developmental in order to see the functional impacts of this chronic odor association treatment.

Contributors

Agent

Created

Date Created
  • 2017-05

134132-Thumbnail Image.png

The Youth Soccer Development Landscape in Europe vs. America: How the U.S. Can Improve Men's Soccer

Description

Why is it that soccer, the world's most popular sport for almost a century, has yet to become established in the world's most ethnically diverse nation? This question is especially

Why is it that soccer, the world's most popular sport for almost a century, has yet to become established in the world's most ethnically diverse nation? This question is especially relevant today given the recent U.S. Men's National Team (ranked 28th in the world) loss to the lowly Trinidad & Tobago (ranked 99th), thus failing to qualify for the FIFA World Cup for the first time since 1986. This represents a huge disappointment for the USMNT since they compete in CONCACAF, arguably the easiest region to succeed. The Icelandic National Team, on the other hand, recently secured their World Cup spot despite having a population of 330,000 and competing in UEFA, which is debatably the hardest region to qualify. This disastrous shortcoming by the USMNT represents the fact that the American system is flawed, and I painstakingly wanted to know why. I reasoned that good teams are made up of good players; good players must stem from a good foundation, which leads to my topic. Because the soccer development landscape differs across continents, this thesis contains a macro-level analysis of the youth models in Europe vs. America and explains how the U.S. can improve. Elite European bodies tend to be more established organizationally, have an abundance of resources, and is surrounded by a culture that praises the sport. While soccer in America is relatively new, often lacks proper resources, and competes in a society that favors multiple other sports. This thesis will elaborate on these differences through the example of the FC Barcelona Youth Academy representing Europe, paralleled to what many consider the best American program: FC Dallas Academy. An assessment will also be included regarding the Icelandic model of player development due to the recent success of their National Teams. Through this smaller comparison representing the larger issue, I will address the opportunity in this moment and how the U.S. can improve. This report will also focus on the men's game because the incredible success of American women at soccer is a very different story that warrants a whole other project. I gathered a majority of my project findings through the use of various books, online resources, academic journals, and data reports. This research has led to the conclusion that there are many factors that determine whether a group is successful at soccer. In the short term, American players should compete abroad if possible in order to train among the world's best. But in an effort to improve at a grassroots level, the United States should focus on providing the basic necessities, promoting an effective sophistication of soccer, and addressing issues that stem from pay-to-play. All of these subjects will be discussed at great lengths below.

Contributors

Created

Date Created
  • 2017-12

135081-Thumbnail Image.png

Last Hymn

Description

Last Hymn was created by the team of Tyler Pinho, Jefferson Le, and Curtis Spence with the desire to create an eccentric Role Playing Game focused on the exploration of

Last Hymn was created by the team of Tyler Pinho, Jefferson Le, and Curtis Spence with the desire to create an eccentric Role Playing Game focused on the exploration of a strange, dying world. Battles in the game are based off of rhythm games like Dance Dance Revolution using a procedural generation algorithm that makes every encounter unique. This is then complemented with the path system where each enemy has unique rhythm patterns to give them different types of combat opportunities. In Last Hymn, the player arrives on a train at the World's End Train Station where they are greeted by a mysterious figure and guided to the Forest where they witness the end of the world and find themselves back at the train station before they left for the Forest. With only a limited amount of time per cycle of the world, the player must constantly weigh the opportunity cost of each decision, and only with careful thought, conviction, and tenacity will the player find a conclusion from the never ending cycle of rebirth. Blending both Shinto architecture and modern elements, Last Hymn used a "fantasy-chic" aesthetic in order to provide memorable locations and dissonant imagery. As the player explores they will struggle against puzzles and dynamic, rhythm based combat while trying to unravel the mystery of the world's looping time. Last Hymn was designed to develop innovative and dynamic new solutions for combat, exploration, and mapping. From this project all three team members were able to grow their software development and game design skills, achieving goals like improved level design, improved asset pipelines while simultaneously aiming to craft an experience that will be unforgettable for players everywhere.

Contributors

Agent

Created

Date Created
  • 2016-12

133808-Thumbnail Image.png

The Dutch Dukeout: Honoring an Everyday Hero

Description

The "Dutch Dukeout" is a memorial, community engagement venture founded by Scott Fitzgerald and Sam Minton. The event was also supported and facilitated through the help of a third party

The "Dutch Dukeout" is a memorial, community engagement venture founded by Scott Fitzgerald and Sam Minton. The event was also supported and facilitated through the help of a third party member, Dylan Bryant. The "Dutch Dukeout" will continue annually, as an opportunity for Brophy College Preparatory alumni and current students to come together and connect. This venture also exists to celebrate and honor the life and legacy of Fr. Harry "Dutch" Olivier, a former, prominent faculty member of Brophy. Additionally, the "Dutch Dukeout" aims to raise money to support the Brophy Scholarship Foundation, a resource for current Brophy students to offset the financial burden it costs to attend the prominent college preparatory. Foremost, the "Dutch Dukeout" flag football tournament provides a powerful way for Brophy Alumni to reconnect with their school. By communicating and participating with graduates from various classes, alumni have an opportunity to provide valuable life lessons and share personal stories with the youth, as well as bond over their shared experience at Brophy. For a school that is able to continually develop community leaders and social activists, the "Dutch Dukeout" provides a platform for collaboration and inspiration for everyone who participates. By raising money to support the Brophy Scholarship Foundation and providing an opportunity for alumni to engage in their community, the "Dutch Dukeout" is an event that truly embodies Fr. Olivier's values and beliefs. This thesis report documents the ideas, work and efforts that were completed to launch and then ensure the success and longevity of the venture. It also serves as an example for future social entrepreneurs who aim to make a difference in communities of their own.

Contributors

Agent

Created

Date Created
  • 2018-05

130992-Thumbnail Image.png

A Framework for Designing Primary Education Technology for Resource Constrained Regions

Description

This paper outlines a responsible innovation framework to evaluate technologies designed for education. Traditionally, technologies being implemented for development of education come from foreign nations with less cultural understanding of

This paper outlines a responsible innovation framework to evaluate technologies designed for education. Traditionally, technologies being implemented for development of education come from foreign nations with less cultural understanding of the needs of the country they are trying to serve. This framework outlines categories that impact the success or failure of an educational technology. The framework is explained and then applied to the SolarSPELL case; an offline digital library designed to bring information to resource constrained areas around the world. The purpose of this research is to explore the factors determining success and failure of educational technology projects and design a framework that can be used moving forward to assess projects prior to the final implementation stage to encourage more successful projects. The framework designed in this research proved useful for evaluating educational technology designed for resource constrained areas.

Contributors

Created

Date Created
  • 2020-12

135927-Thumbnail Image.png

Steps for Improving Quality of Placemaking on Roosevelt Row

Description

Surrounded by a developmental boom in downtown Phoenix, Roosevelt Row fights to maintain the local art influence and historic character. An earthy community of street artists, coffee drinkers, band tees,

Surrounded by a developmental boom in downtown Phoenix, Roosevelt Row fights to maintain the local art influence and historic character. An earthy community of street artists, coffee drinkers, band tees, nose rings, vinyl collectors and rolled denim, the people are facing dramatic urbanization. The hum of drills, hammers, cranes and alarms sound throughout the viscidity, echoing the construction of a new era downtown. In the interest of better understanding the developmental process, resident needs and community, this research project evaluates successful public spaces and similar downtown areas in the United States, synthesized their elements of prosperity in comparison to general attributes of quality public spaces, and implemented the concepts and ideas into Roosevelt Row. This provided the researcher with knowledge of quality public spaces, why public space is important, and how placemaking is routinely accomplished. This also equipped the researcher with the tools to participate in ethnography and collect observational data to learn about Roosevelt Row. The researcher then combined learned material with what she observed on the Row, to condense the artists' district developmental needs into nine proposals for bettering the Row in the immediate, near and long-term future. The study begs to answer the question: is Roosevelt Row a Place or a place? Observation, residential and visitor engagement with the space; locality, pleasurability, inclusiveness and safety of the public spaces; and relationship between residents and quality of space all contribute to the space's qualifications. While Roosevelt Row has the potential and assets to become a Place, especially if the nine proposals are implemented. However, at the time of research, the space is between place and Place.

Contributors

Created

Date Created
  • 2015-12

131604-Thumbnail Image.png

Hypoxia Inducible Factor Accumulation in 3rd Instar Drosophila melanogaster

Description

Hypoxia-responses help coordinate the growth of oxygen-transporting tissues with the growth of other tissues during development. In Drosophila, hypoxia strongly affects development with flies being reared in a low oxygen

Hypoxia-responses help coordinate the growth of oxygen-transporting tissues with the growth of other tissues during development. In Drosophila, hypoxia strongly affects development with flies being reared in a low oxygen environment showing smaller body sizes and diminished tracheal growth. The primary regulator of cellular hypoxic-responses is the hypoxia-inducible factor (HIF), and under normoxic conditions, HIF-alpha is hydroxylated by prolyl hydroxylase domain (PHD) on a proline residue inside the alpha leading to the proteins proteasome degradation downstream. However, in response to reduced oxygen, cells accumulate HIF- alpha, which then joins with the constituent HIF-beta in the cytosol, forming a HIF- alpha/beta heterodimer. Which, in turn, enters the nucleus and binds to hypoxic response elements, activating the hypoxic response genes. Hyperoxia has recently been shown to stimulates metabolic rates only at the last stage Drosophila's larval development (L3), indicating oxygen limitation occurs towards the end of development. Green fluorescent protein (GFP) was added to the oxygen-dependent domain of Drosophila HIF- Alpha (Sima) and a monomeric red fluorescent protein with a nuclear localization signal (mRFP-nls) was added to a protein under the same ubiquitin-69E promoter but is not affected by changing O2 levels. Using a Leica SP5 AOBS Spectral Confocal, third instar larvae were analyzed at the cellular level with attention focused on HIF- signaling in the central nervous system (CNS). L3 Drosophila were divided into groups of 0-12h, 12-24h, 24-48h, and 48-60h corresponding to their development. In each group, flies were either treated for 10-12 hours in 5% O2 or were left normoxic before fixation. What was overwhelmingly found is that HIF-signaling was most prominent during their early development (0-12h), with a significant decline as age increased (P=<0.001). There was also an observed hypoxic effect as animals treated in lower oxygen concentrations had significantly higher HIF signaling (P=<0.001). However, this effect still declines as larvae continued developing. This data supports the idea that internal hypoxia does not become severe during late third instar growth but may occur during the actual molt of the flies.

Contributors

Agent

Created

Date Created
  • 2020-05

Childhood Trauma: The Single Greatest Unaddressed Public Health Threat

Description

Adverse Childhood Events (ACEs) are defined as experiences during childhood that caused extensive stress and can include events such as abuse, disasters, violence, or neglect. These ACEs are shown to

Adverse Childhood Events (ACEs) are defined as experiences during childhood that caused extensive stress and can include events such as abuse, disasters, violence, or neglect. These ACEs are shown to have great effects on the psychological as well as physiological well-being of the individual into adulthood, and have been linked to disorders such as chronic obstructive pulmonary disease (COPD), cancer, obesity, alcoholism, hallucinations, and post-traumatic stress disorder (PTSD). For this reason, ACEs have been considered "the single greatest unaddressed public health threat facing our nation today" (Kalmakis & Chandler, 2015). Nurses are in a unique place in caring for individuals in which they can screen patients for adverse childhood experiences and trauma and teach strength-based resilience in order to interrupt this disease progression. As a part of our thesis, we created an educational module to inform nursing students of this study.

Contributors

Created

Date Created
  • 2016-12