Homelessness has a history of existing as a misunderstood condition involving stereotypes, stigmas and assumptions. In fact, the combination of acute-care medical professionals with patients of chronic illness and chronic homelessness can lead to incongruity of attitudes. These mindsets have the potential to affect the care homeless individuals receive in the emergency department (ED) and impact their intentions to seek medical help in the future (Ugarriza & Fallon, 1994, pp. 26). Furthermore, homeless individuals account for 54.5% of all ED visits in the United States (Kushel et al., 2002). The author conducted a qualitative descriptive study of 10 in-person interviews with homeless individuals in the downtown Phoenix, AZ area. The objective was to determine homeless individuals' perceptions of welcomeness and unwelcomeness by emergency department staff. Findings support significantly unwelcome experiences in the ED and negative perceptions of ED staff through repeating concepts of dehumanization, dismissal, stereotypes and discrimination. Further research is needed to create interventions for improving perceptions of ED staff, promoting health and preventing illness in the homeless population, and reducing ED visits by homeless individuals.