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- All Subjects: Divorce
- Creators: College of Letters and Sciences
- Member of: Theses and Dissertations
- Resource Type: Text
Description
Is it possible to treat the mouth as a natural environment, and determine new methods to keep the microbiome in check? The need for biodiversity in health may suggest that every species carries out a specific function that is required to maintain equilibrium and homeostasis within the oral cavity. Furthermore, the relationship between the microbiome and its host is mutually beneficial because the host is providing microbes with an environment in which they can flourish and, in turn, keep their host healthy. Reviewing examples of larger scale environmental shifts could provide a window by which scientists can make hypotheses. Certain medications and healthcare treatments have been proven to cause xerostomia. This disorder is characterized by a dry mouth, and known to be associated with a change in the composition, and reduction, of saliva. Two case studies performed by Bardow et al, and Leal et al, tested and studied the relationships of certain medications and confirmed their side effects on the salivary glands [2,3]. Their results confirmed a relationship between specific medicines, and the correlating complaints of xerostomia. In addition, Vissink et al conducted case studies that helped to further identify how radiotherapy causes hyposalivation of the salivary glands [4]. Specifically patients that have been diagnosed with oral cancer, and are treated by radiotherapy, have been diagnosed with xerostomia. As stated prior, studies have shown that patients having an ecologically balanced and diverse microbiome tend to have healthier mouths. The oral cavity is like any biome, consisting of commensalism within itself and mutualism with its host. Due to the decreased salivary output, caused by xerostomia, increased parasitic bacteria build up within the oral cavity thus causing dental disease. Every human body contains a personalized microbiome that is essential to maintaining health but capable of eliciting disease. The Human Oral Microbiomics Database (HOMD) is a set of reference 16S rRNA gene sequences. These are then used to define individual human oral taxa. By conducting metagenomic experiments at the molecular and cellular level, scientists can identify and label micro species that inhabit the mouth during parasitic outbreaks or a shifting of the microbiome. Because the HOMD is incomplete, so is our ability to cure, or prevent, oral disease. The purpose of the thesis is to research what is known about xerostomia and its effects on the complex microbiome of the oral cavity. It is important that researchers determine whether this particular perspective is worth considering. In addition, the goal is to create novel experiments for treatment and prevention of dental diseases.
ContributorsHalcomb, Michael Jordan (Author) / Chen, Qiang (Thesis director) / Steele, Kelly (Committee member) / Barrett, The Honors College (Contributor) / College of Letters and Sciences (Contributor)
Created2015-05
Description
With divorce rates rising (Kennedy & Ruggles, 2014), it is important to consider the impact of parental marital status on children and adolescents. In this study, we looked at whether children's relationships with their parents differ based on their parents being married or divorced/separated. We hypothesized that a child's perceived relationship with their parents would be significantly influenced by parental marital status, such that those whose parents are divorced will demonstrate a negative relationship with the perception of their parents. Using data collected from the longitudinal New England Study of Suburban Youth (NESSY), we ran correlational analyses as well as an analysis of variance (ANOVA) to determine whether different aspects of attachment (Alienation, Communication, and Trust), measured with the Inventory of Parent and Peer Attachment \u2014 Revised for Children (IPPA-R) were significantly linked to parental marital status (Luthar & Barkin, 2012). Using our sample size of 489 students in the twelfth grade, we divided the groups into children with married parents (414) and children with divorced or separated parents (75). An ANOVA produced a significant difference between children's perceived relationship with their father and parental marital status; the adolescents' perception of the father's Alienation, Communication, and Trust were negatively associated with divorce. However, the child's perceived relationship with their mother was similar across both groups. These results suggest further research is needed to determine the effects of a child's perception of their relationship with their father during development, in particular in situations when parents have divorced before high school graduation.
ContributorsSmith, Paulina A. (Co-author) / Smith, Travis W. (Co-author) / Luthar, Suniya S. (Thesis director) / Ciciolla, Lucia (Committee member) / Curlee, Alexandria (Committee member) / School of Social Transformation (Contributor) / Department of Psychology (Contributor) / College of Letters and Sciences (Contributor) / Barrett, The Honors College (Contributor)
Created2016-05