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Birds have unusually high plasma glucose concentrations compared to mammals of similar size despite their high metabolic rate. While birds use lipids as their main source of energy, it is still unclear how and why they maintain high plasma glucose concentrations. To investigate a potential underlying mechanism, this study looks

Birds have unusually high plasma glucose concentrations compared to mammals of similar size despite their high metabolic rate. While birds use lipids as their main source of energy, it is still unclear how and why they maintain high plasma glucose concentrations. To investigate a potential underlying mechanism, this study looks at the role of lipolysis in glucose homeostasis. The purpose of this study is to examine the effects of decreased glycerol availability (through inhibition of lipolysis) on plasma glucose concentrations in mourning doves. The hypothesis is that decreased availability of glycerol will result in decreased production of glucose through gluconeogenesis leading to reduced plasma glucose concentrations. In the morning of each experiment, mourning doves were collected at the Arizona State University Tempe campus, and randomized into either a control group (0.9% saline) or experimental group (acipimox, 50mg/kg BM). Blood samples were collected prior to treatment, and at 1, 2, and 3 hours post-treatment. At 3 hours, doves were euthanized, and tissue samples were collected for analysis. Acipimox treatment resulted in significant increases in blood glucose concentrations at 1 and 2 hours post- treatment as well as renal triglyceride concentrations at 3 hours post-treatment. Change in plasma free glycerol between 0h and 3h followed an increasing trend for the acipimox treated animals, and a decreasing trend in the saline treated animals. These results do not support the hypothesis that inhibition of lipolysis should decrease blood glycerol and blood glucose levels. Rather, the effects of acipimox in glucose homeostasis appear to differ significantly between birds and mammals suggesting differing mechanisms for glucose homeostasis.
ContributorsKouteib, Soukaina (Author) / Sweazea, Karen (Thesis director) / Deviche, Pierre (Committee member) / Chandler, Douglas (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2015-05
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The transition to college has been identified as a vulnerable period for weight gain and the onset of obesity. Research has shown that the gut microbiota is different in obese compared to lean individuals, but a period of weight gain has never been studied in free-living individuals. The objective of

The transition to college has been identified as a vulnerable period for weight gain and the onset of obesity. Research has shown that the gut microbiota is different in obese compared to lean individuals, but a period of weight gain has never been studied in free-living individuals. The objective of this longitudinal, observational study was to assess the association between changes in the intestinal microbiota and weight-related outcomes in healthy college students living in on-campus dormitories at Arizona State University (n=39). Anthropometric measures and fecal samples were collected at the beginning and end of the school year, and microbial relative abundance for A. muciniphila, F. prausnitzii, R. gnavus, and L. acidophilus was measured through qPCR analyses. In this population, body mass index (BMI) and waist circumference (WC) increased by 0.97 ± 1.28 kg/m2 and 2.64 ± 4.90 cm, respectively. Wilcoxon-Rank tests revealed that R. gnavus fold change was significantly different between groups of weight loss/maintenance and weight gain ≥ 5% body weight (0.14 [-0.21, 0.64], n=24 vs. -0.14 [-0.92, 0.05], n=15, respectively; p=0.028). Correlation analyses suggested a significant negative association between A. muciniphila fold change and both % WC change and % BMI change (r= -0.66; p<0.01 and r= -0.33; p=0.04, respectively). However, multivariate regression analysis controlling for sex and race/ethnicity showed a significant association between A. muciniphila and % WC change, but not % BMI change (R2= 0.53; p<0.01 and R2= 0.24; p=0.15). F. prausnitzii was not associated with weight-related outcomes in this sample. L. acidophilus was excluded from study analyses after subsequent qPCR trials revealed no amplification in participant samples. Overall, this was the first study to show a relationship between A. muciniphila fold change and weight-related outcomes over a period of weight gain. Specifically, A. muciniphila was strongly negatively associated with WC in this sample. Further research is needed to more accurately describe these associations and potential mechanisms associated with the shift in gut microbiota observed with weight gain. Findings from future research may be used to develop interventions for college students aiming to shift the gut microbiota to prevent weight gain.
ContributorsJourney, Elizabeth (Author) / Whisner, Corrie M (Thesis advisor) / Bruening, Meredith (Committee member) / Sweazea, Karen (Committee member) / Arizona State University (Publisher)
Created2017
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Description

Studies over the past years have collected data on the opinions of women in the workforce related to family planning and societal norms (Buddhapriya, 2009). However, these studies do not address the opinions of college students, the majority of whom have not yet entered the workforce yet, may have strong

Studies over the past years have collected data on the opinions of women in the workforce related to family planning and societal norms (Buddhapriya, 2009). However, these studies do not address the opinions of college students, the majority of whom have not yet entered the workforce yet, may have strong opinions about whether or not career ambitions and the desire for children are mutually exclusive. In addition, these studies mainly focus on the hardships of women already in the workforce, rather than to understand how to broaden the workforce to accommodate women before entering motherhood. Therefore, to encourage mothers in the workforce to strive for high professional achievement, it is important to first encourage those making life-changing decisions based on degree choice in college. In doing this, 111 Arizona State University (ASU) students of all years, gender, and college choice were surveyed to better understand the difference between men's and women’s opinions on family planning in relation to career. The results of the survey concluded that more women have not let family planning affect their choice of major and career aspirations. Although previous studies have shown that a job affects motherhood in the professional aspect, this does not seem to be a reason to alter career choices.

ContributorsBowman, Hannah L (Author) / Kappes, Janelle (Thesis director) / Sullivan-Detheridge, Julie (Committee member) / School of Sustainability (Contributor) / Department of Information Systems (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Description

Living a healthy and balanced life can be difficult for college students at Arizona State<br/>University due to the barrier of high cost of healthy food. To understand more about this problem<br/>we conducted research on the Tempe campus through surveys and virtual focus groups. We<br/>discovered that the cost of healthy food

Living a healthy and balanced life can be difficult for college students at Arizona State<br/>University due to the barrier of high cost of healthy food. To understand more about this problem<br/>we conducted research on the Tempe campus through surveys and virtual focus groups. We<br/>discovered that the cost of healthy food is one of the main barriers preventing students from<br/>eating healthy. We also learned that the students would be more willing to eat healthier if they<br/>could access healthy foods at a more reasonable price. Our solution to this problem was Eunoia,<br/>a service that allows students to receive discounts on healthy food and incentivize them to eat<br/>healthier in the future. Our company creates an innovative relationship between our customers,<br/>their private health insurance companies and local grocery stores throughout the Phoenix Metro<br/>area. Students at Arizona State University will be able to purchase healthy food items discounted<br/>by up to 30%. These discounts will be funded by their health insurance companies as well as the<br/>local grocery stores they purchase from. Our business model allows our customers to live<br/>healthier lives while also providing value to partnered health insurance companies and grocery<br/>stores. Once we established our business model, we spoke with students at Arizona State<br/>University and representatives from health insurance companies. Through these demographics,<br/>we received positive feedback and early traction with our idea. Our goal is to be able to<br/>implement our product in the Arizona State University community and then expand this product<br/>into a more general market to help all people live a pure and balanced life.

ContributorsEvans, Hayden Curtis (Co-author) / Wijesinghe, Megan (Co-author) / Zimprich, Preston (Co-author) / Byrne, Jared (Thesis director) / Hall, Rick (Committee member) / School of Molecular Sciences (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
Description

This thesis will bring together students to engage in entrepreneurship by finding, measuring and sharing strategic market opportunities. From a student’s perspective, it will take a deep dive into the world of startup ecosystems, markets and trends utilizing both qualitative and quantitative market research techniques. The information gathered has been

This thesis will bring together students to engage in entrepreneurship by finding, measuring and sharing strategic market opportunities. From a student’s perspective, it will take a deep dive into the world of startup ecosystems, markets and trends utilizing both qualitative and quantitative market research techniques. The information gathered has been curated into a productive, meaningful manner, through a report titled “The State of Startups: A Student Perspective.” <br/> The first key theme of this thesis is that market intelligence can be a powerful tool. The second key theme is the power of knowledge implementation towards competitive strategies. The first section of the thesis will focus on identifying and understanding the current “startup” landscape as a basis on which to build strategic and impactful business decisions. This will be accomplished as the team conducts a landscape analysis focused on the student perspective of the student-based North American “entrepreneurial” ecosystem. The second section of the thesis will focus specifically on the personal experiences of student startup founders. This will be accomplished through the analysis of interviews with founders of the startups researched from the first section of the thesis. This will provide us with a direct insight into the student perspective of the student-based North American “entrepreneurial” ecosystem.

ContributorsCallahan, Ryan (Co-author) / Forshey, Cecilia (Co-author) / Hybert, Jacob (Co-author) / Minic, Jacob (Co-author) / Rudick, Justin (Co-author) / Byrne, Jared (Thesis director) / Curtiss, Ian (Committee member) / Olsen, Douglas (Committee member) / Department of Economics (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Barrett, The Honors College (Contributor)
Created2021-05
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Description
ABSTRACT

Background. College students’ modifiable health behaviors, including unhealthful eating patterns, predispose them to risk for future cardiometabolic conditions.

Purpose. This novel 8-week randomized control parallel-arm study compared the effects of a daily 18-hour Time-Restricted Feeding protocol vs. an 8-hour fast on diet quality in college students. Secondary outcomes were resting

ABSTRACT

Background. College students’ modifiable health behaviors, including unhealthful eating patterns, predispose them to risk for future cardiometabolic conditions.

Purpose. This novel 8-week randomized control parallel-arm study compared the effects of a daily 18-hour Time-Restricted Feeding protocol vs. an 8-hour fast on diet quality in college students. Secondary outcomes were resting morning blood pressure, biomarkers of glucose regulation, biomarkers of lipid metabolism, and anthropometric measures.

Methods. Eighteen healthy college students (age = 23 ± 4 years; BMI = 23.2 ± 2.3 kg/m2; MET = 58.8 ± 32.9 min/wk) completed this study. Participants were randomized to a daily 18-hour fasting protocol (Intervention; n = 8) or a daily 8-hour fasting protocol (Control; n = 10) for eight weeks. One ‘cheat’ day was permitted each week. Outcomes were measured at weeks 0 (baseline), 4, and 8. A non-parametric Mann Whitney U test was used to compare the week 4 change from baseline between groups. Statistical significance was set at p≤0.05.

Results. Diet quality (p = 0.030) and body weight (p = 0.016) improved from baseline to week 4 for the INV group in comparison to the CON group. The data suggest these improvements may be related to reductions in snacking frequency and increased breakfast consumption. Fasting blood glucose and hip circumference tended to improve for the INV group in comparison to the CON group (p = 0.091 and p = 0.100). However, saturated fat intake tended to increase in the INV group in comparison to the CON group (p = 0.064). Finally, there were no treatment differences between groups (p>0.05) for the 4-week change in total calories, dietary vitamin C, added sugars, resting systolic blood pressure, resting diastolic blood pressure, insulin, homeostatic model assessment for insulin resistance (HOMA-IR), low-density lipoprotein (LDL) cholesterol, triglycerides, high-density lipoprotein (HDL) cholesterol, waist circumference, or MET.

Conclusion. These data, although preliminary, suggest that the 18-hour fasting protocol was effective for improving diet quality and reducing weight in comparison to the 8-hour fasting protocol in healthy college students. Future intervention trials will need to confirm these findings and determine the long-term relevance of these improvements for health outcomes.
ContributorsMayra, Selicia (Author) / Johnston, Carol (Thesis advisor) / Sears, Dorothy (Committee member) / Swan, Pamela (Committee member) / Sweazea, Karen (Committee member) / Wharton, Christopher (Christopher Mack), 1977- (Committee member) / Arizona State University (Publisher)
Created2020
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Description
College graduates are having a challenging time attaining jobs upon graduation as most companies require years of experience. There are resources available online, however they are targeting different aspects. Forming a solution to this problem is an idea, Crove, a website tool that can be used by students applying to

College graduates are having a challenging time attaining jobs upon graduation as most companies require years of experience. There are resources available online, however they are targeting different aspects. Forming a solution to this problem is an idea, Crove, a website tool that can be used by students applying to companies as well as recruiters searching for the right candidate. As Crove becomes the mediator between employers and employees, it will formulate a smooth form of interaction among the two parties. With Crove, students have the ability to display their resumes with skills in addition to their non-job related skills, such as hobbies, spotify playlist, etc. This will help recruiters truly understand the potential employee outside of technical skills. Furthermore, the student will have the opportunity to upload a short video about themselves; this can help recruiters get a sense of the candidate's personality and in some cases, help with the behavioral part of the interview process. This unique platform benefits both employers and employees with its distinctive feature.
ContributorsBates, Noah (Author) / Singh, Anjali (Co-author) / Coleman, Ethan (Thesis director) / Hightower, Dimetrius (Committee member) / Barrett, The Honors College (Contributor) / Dean, W.P. Carey School of Business (Contributor)
Created2022-05
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Description
This thesis considers various studies related to how COVID-19 has affected college students worldwide. This project provides an early examination of the literature in an effort to identify emerging themes, common global experiences, and areas still to be studied. First this project looks at how COVID-19 has exacerbated technological inequities,

This thesis considers various studies related to how COVID-19 has affected college students worldwide. This project provides an early examination of the literature in an effort to identify emerging themes, common global experiences, and areas still to be studied. First this project looks at how COVID-19 has exacerbated technological inequities, including the impacts of the digital divide on college students’ educations. This project shows how the lack of access to technology and the digital divide has deprived students of educational opportunities and has impacted their overall quality of education. Second, this project looks at the mental health impacts of the pandemic on college students. College students are already a very vulnerable population to begin with, and COVID-19 further exacerbated mental health issues among these students. Third, this project looks at findings about gender differences and the impacts of COVID-19 based on gender. This project also explores the positive impacts of the pandemic, and finally concludes with ideas for future research going forward, as well as solutions to the problems addressed in the project. This project reviews literature from a global perspective. Many of the studies in this project are taken from international university student populations, as it is important to compare how university students worldwide reacted to and were impacted by the pandemic. Taking this global view into perspective is necessary to formulate methods of action in the possible occurrence of a future health crisis of this scale.
ContributorsVan Tilborg, Natalie (Author) / O'Flaherty, Katherine (Thesis director) / Rendell, Dawn (Committee member) / Barrett, The Honors College (Contributor) / Dean, W.P. Carey School of Business (Contributor) / Department of Supply Chain Management (Contributor) / Department of Marketing (Contributor)
Created2022-05