Matching Items (8)
Description
This project features three new pieces for oboe commissioned from three different composers. Each piece explores styles and/or instrumentations that are less common in the current body of repertoire. These pieces are Scenes for Charlie by Bryan Kennard, Love’s Last Gift by Thomas Juneau, and But Joy Comes in the

This project features three new pieces for oboe commissioned from three different composers. Each piece explores styles and/or instrumentations that are less common in the current body of repertoire. These pieces are Scenes for Charlie by Bryan Kennard, Love’s Last Gift by Thomas Juneau, and But Joy Comes in the Morning by William Brusick. A performance guide has been included for each piece, providing tips and suggestions for musicians wanting to perform these pieces in the future. In addition to the performance guide, each composer answered a list of interview questions to provide background information and give insight into their compositional process. Accompanying this document are recordings performed by the author.
ContributorsSummers, Season (Author) / Schuring, Martin (Thesis advisor) / Gardner, Joshua (Committee member) / Norton, Kay (Committee member) / Arizona State University (Publisher)
Created2021
Description

On January 5, 2020, the World Health Organization (WHO) reported on the outbreak of pneumonia of unknown cause in Wuhan, China. Two weeks later, a 35-year-old Washington resident checked into a local urgent care clinic with a 4-day cough and fever. Laboratory testing would confirm this individual as the first

On January 5, 2020, the World Health Organization (WHO) reported on the outbreak of pneumonia of unknown cause in Wuhan, China. Two weeks later, a 35-year-old Washington resident checked into a local urgent care clinic with a 4-day cough and fever. Laboratory testing would confirm this individual as the first case of the novel coronavirus in the U.S., and on January 20, 2020, the Center for Disease Control (CDC) reported this case to the public. In the days and weeks to follow, Twitter, a social media platform with 450 million active monthly users as of 2020, provided many American residents the opportunity to share their thoughts on the developing pandemic online. Social media sites like Twitter are a prominent source of discourse surrounding contemporary political issues, allowing for direct communication between users in real-time. As more population centers around the world gain access to the internet, most democratic discussion, both nationally and internationally, will take place in online spaces. The activity of elected officials as private citizens in these online spaces is often overlooked. I find the ability of publics—which philosopher John Dewey defines as groups of people with shared needs—to communicate effectively and monitor the interests of political elites online to be lacking. To best align the interests of officials and citizens, and achieve transparency between publics and elected officials, we need an efficient way to measure and record these interests. Through this thesis, I found that natural language processing methods like sentiment analyses can provide an effective means of gauging the attitudes of politicians towards contemporary issues.

ContributorsHowell, Nicholas (Author) / Voorhees, Matthew (Thesis director) / Schmidt, Peter (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Statistical Sciences (Contributor) / School of Life Sciences (Contributor)
Created2023-05
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Description

Since the beginning of the COVID-19 pandemic, telemedicine usage in America has experienced extreme peaks as a method of maintaining social distancing for medical staff and patients. While there have been numerous significant positive effects from increasing this practice, there are also significant risks to be explored. Patients and physicians

Since the beginning of the COVID-19 pandemic, telemedicine usage in America has experienced extreme peaks as a method of maintaining social distancing for medical staff and patients. While there have been numerous significant positive effects from increasing this practice, there are also significant risks to be explored. Patients and physicians have been navigating new technology, new protocols, and new dynamics at a high rate. Doctors using telemedicine are required to rely more heavily on their judgment with less data than usual to support their hypotheses. This results in a wide variety of potential complications that can be detrimental to patients and physicians alike. Though negative outcomes are not nearly the majority, it is clear that for telemedicine to function at its fullest capacity, the limitations of its technology must be defined and communicated. A survey was distributed to physicians currently practicing telemedicine to understand more about the usage increase in telemedicine and the incidence rates of telemedicine-related complications. The results showed that although the impact of telemedicine has been largely positive, there certainly are risks that must be considered and prepared for. Thus, it is the responsibility of healthcare systems to ensure that their policies are current and appropriate in proportion to their usage of telemedicine to better protect and prepare patients and doctors for this new frontier of medicine.

ContributorsRogers, Hannah (Author) / Lynch, John (Thesis director) / Grimaldi, Lisa (Committee member) / Barrett, The Honors College (Contributor) / School of Life Sciences (Contributor)
Created2022-05
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Description
The development of biosensing platforms not only has an immediate lifesaving effect but also has a significant socio-economic impact. In this dissertation, three very important biomarkers with immense importance were chosen for further investigation, reducing the technological gap and improving their sensing platform.Firstly, gold nanoparticles (AuNP) aggregation and sedimentation-based assays

The development of biosensing platforms not only has an immediate lifesaving effect but also has a significant socio-economic impact. In this dissertation, three very important biomarkers with immense importance were chosen for further investigation, reducing the technological gap and improving their sensing platform.Firstly, gold nanoparticles (AuNP) aggregation and sedimentation-based assays were developed for the sensitive, specific, and rapid detection of Ebola virus secreted glycoprotein (sGP)and severe acute respiratory syndrome coronavirus 2 (SARS-COV2) receptor-binding domain (RBD) antigens. An extensive study was done to develop a complete assay workflow from critical nanobody generation to optimization of AuNP size for rapid detection. A rapid portable electronic reader costing (<$5, <100 cm3), and digital data output was developed. Together with the developed workflow, this portable electronic reader showed a high sensitivity (limit of detection of ~10 pg/mL, or 0.13 pM for sGP and ~40 pg/mL, or ~1.3 pM for RBD in diluted human serum), a high specificity, a large dynamic range (~7 logs), and accelerated readout within minutes. Secondly, A general framework was established for small molecule detection using plasmonic metal nanoparticles through wide-ranging investigation and optimization of assay parameters with demonstrated detection of Cannabidiol (CBD). An unfiltered assay suitable for personalized dosage monitoring was developed and demonstrated. A portable electronic reader demonstrated optoelectronic detection of CBD with a limit of detection (LOD) of <100 pM in urine and saliva, a large dynamic range (5 logs), and a high specificity that differentiates closely related Tetrahydrocannabinol (THC). Finally, with careful biomolecular design and expansion of the portable reader to a dual-wavelength detector the classification of antibodies based on their affinity to SARS-COV2 RBD and their ability to neutralize the RBD from binding to the human Angiotensin-Converting Enzyme 2 (ACE2) was demonstrated with the capability to detect antibody concentration as low as 1 pM and observed neutralization starting as low as 10 pM with different viral load and variant. This portable, low-cost, and versatile readout system holds great promise for rapid, digital, and portable data collection in the field of biosensing.
ContributorsIkbal, Md Ashif (Author) / Wang, Chao (Thesis advisor) / Goryll, Michael (Committee member) / Zhao, Yuji (Committee member) / Wang, Shaopeng (Committee member) / Arizona State University (Publisher)
Created2022
Description
Contaminated aerosols and micro droplets are easily generated by infected hosts through sneezing, coughing, speaking and breathing1-3 and harm humans’ health and the global economy. While most of the efforts are usually targeted towards protecting individuals from getting infected,4 eliminating transmissions from infection sources is also important to prevent disease

Contaminated aerosols and micro droplets are easily generated by infected hosts through sneezing, coughing, speaking and breathing1-3 and harm humans’ health and the global economy. While most of the efforts are usually targeted towards protecting individuals from getting infected,4 eliminating transmissions from infection sources is also important to prevent disease transmission. Supportive therapies for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS CoV-2) pneumonia such as oxygen supplementation, nebulizers and non-invasive mechanical ventilation all carry an increased risk for viral transmission via aerosol to healthcare workers.5-9 In this work, I study the efficacy of five methods for self-containing aerosols emitted from infected subjects undergoing nebulization therapies with a diverse spectrum on Non-Invasive Positive Pressure Ventilator (NIPPV) with oxygen delivery therapies. The work includes five study cases: Case I: Use of a Full-Face Mask with biofilter in bilevel positive airway pressure device (BiPAP) therapy, Case II: Use of surgical mask in High Flow Nasal Cannula (HFNC) therapy, Case III: Use of a modified silicone disposable mask in a HFNC therapy, Case IV: Use of a modified silicone disposable mask with a regular nebulizer and normal breathing, Case V: Use of a mitigation box with biofilter in a BiPAP. We demonstrate that while cases I, III and IV showed efficacies of 98-100%; cases II and V, which are the most commonly used, resulted with significantly lower efficacies of 10-24% to mitigate the dispersion of nebulization aerosols. Therefore, implementing cases I, III and IV in health care facilities may help battle the contaminations and infections via aerosol transmission during a pandemic.
ContributorsShyamala Pandian, Adithya (Author) / Forzani, Erica (Thesis advisor) / Patel, Bhavesh (Committee member) / Xian, Xiaojun (Committee member) / Arizona State University (Publisher)
Created2021
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Description
A factor accounting for the COVID-19 pandemic was added to a generalized linear model to more accurately predict unpaid claims. COVID-19 has affected not just healthcare, but all sectors of the economy. Because of this, whether or not an automobile insurance claim is filed during the pandemic needs to be

A factor accounting for the COVID-19 pandemic was added to a generalized linear model to more accurately predict unpaid claims. COVID-19 has affected not just healthcare, but all sectors of the economy. Because of this, whether or not an automobile insurance claim is filed during the pandemic needs to be taken into account while estimating unpaid claims. Reserve-estimating functions such as glmReserve from the “ChainLadder” package in the statistical software R were experimented with to produce their own results. Because of their insufficiency, a manual approach to building the model turned out to be the most proficient method. Utilizing the GLM function, a model was built that emulated linear regression with a factor for COVID-19. The effects of such a model are analyzed based on effectiveness and interpretablility. A model such as this would prove useful for future calculations, especially as society is now returning to a “normal” state.
ContributorsKossler, Patrick (Author) / Zicarelli, John (Thesis director) / Milovanovic, Jelena (Committee member) / Barrett, The Honors College (Contributor) / School of Mathematical and Statistical Sciences (Contributor)
Created2022-05
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Description

When the Covid-19 virus began to spread worldwide in the spring of 2020, life across the globe changed rapidly. Government restrictions required people to move into prolonged social isolation and the resulting impact of this isolation on mental health has been profound (Brooks et al., 2020). Initial research has begun

When the Covid-19 virus began to spread worldwide in the spring of 2020, life across the globe changed rapidly. Government restrictions required people to move into prolonged social isolation and the resulting impact of this isolation on mental health has been profound (Brooks et al., 2020). Initial research has begun to be conducted to understand the scope of how social isolation and the pandemic have influenced people’s psychological well-being. Thus far there has been a marked increase in depression and anxiety disorders (Eyice Karabacak et al., 2021). Agoraphobia is an anxiety disorder that is characterized by fear and avoidance of certain settings. Undoubtedly, fear and avoidance of certain settings during the pandemic cannot be considered abnormal behavior as it is in line with a normative response to such a threatening phenomenon. This study investigates how normative avoidance of certain settings during the pandemic may have now evolved into fear of the settings themselves. In particular, it tested if the start of the pandemic is associated with the prevalence rate of Agoraphobia. This was done via a retrospective study that uses self-report data to examine whether participants presented symptoms of Agoraphobia prior to the start of the pandemic and if they currently exhibit symptoms of Agoraphobia. In addition to the study, the website designed to host this study also provided mental health resources to participants, in light of the documented increase in mental illness since the start of the pandemic (Brooks et al., 2020).

ContributorsFranke, Jillian (Author) / Peterson, Bria (Co-author) / Clough, Michael (Thesis director) / Lanphier, Erin (Committee member) / Barrett, The Honors College (Contributor) / Civil, Environmental and Sustainable Eng Program (Contributor)
Created2022-05
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Description

This Project Report documents the accomplishments of an extraordinary group of students, faculty, and staff at the Arizona state University, who participated in a year-long, multidisciplinary, first-of-its-kind academic endeavor entitled “The Making of a COVID Lab.” The lab that is the focus of this project is the ASU Biodesign Clinical

This Project Report documents the accomplishments of an extraordinary group of students, faculty, and staff at the Arizona state University, who participated in a year-long, multidisciplinary, first-of-its-kind academic endeavor entitled “The Making of a COVID Lab.” The lab that is the focus of this project is the ASU Biodesign Clinical Testing Laboratory, known simply as the ABCTL.

ContributorsCompton, Carolyn C. (Project director) / Christianson, Serena L. (Project director) / Floyd, Christopher (Project director) / Schneller, Eugene S (Research team head) / Rigoni, Adam (Research team head) / Stanford, Michael (Research team head) / Cheong, Pauline (Research team head) / McCarville, Daniel R. (Research team head) / Dudley, Sean (Research team head) / Blum, Nita (Research team head) / Magee, Mitch (Research team head) / Agee, Claire (Research team member) / Cosgrove, Samuel (Research team member) / English, Corinne (Research team member) / Mattson, Kyle (Research team member) / Qian, Michael (Research team member) / Espinoza, Hale Anna (Research team member) / Filipek, Marina (Research team member) / Jenkins, Landon James (Research team member) / Ross, Nathaniel (Research team member) / Salvatierra, Madeline (Research team member) / Serrano, Osvin (Research team member) / Wakefield, Alex (Research team member) / Calo, Van Dexter (Research team member) / Nofi, Matthew (Research team member) / Raymond, Courtney (Research team member) / Barwey, Ishna (Research team member) / Bruner, Ashley (Research team member) / Hymer, William (Research team member) / Krell, Abby Elizabeth (Research team member) / Lewis, Gabriel (Research team member) / Myers, Jack (Research team member) / Ramesh, Frankincense (Research team member) / Reagan, Sage (Research team member) / Kandan, Mani (Research team member) / Knox, Garrett (Research team member) / Leung, Michael (Research team member) / Schmit, Jacob (Research team member) / Woo, Sabrina (Research team member) / Anderson, Laura (Research team member) / Breshears, Scott (Research team member) / Majhail, Kajol (Research team member) / Ruan, Ellen (Research team member) / Smetanick, Jennifer (Research team member) / Bardfeld, Sierra (Research team member) / Cura, Joriel (Research team member) / Dholaria, Nikhil (Research team member) / Foote, Hannah (Research team member) / Liu, Tara (Research team member) / Raymond, Julia (Research team member) / Varghese, Mahima (Research team member)
Created2021