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Endocrine disruptors are chemicals that interact with the hormone system to negative effect. They ‘disrupt’ normal processes to cause diseases like vaginal cancer and obesity, reproductive issues like t-shaped uteri and infertility, and developmental abnormalities like spina bifida and cleft palate. These chemicals are ubiquitous in our daily lives, components

Endocrine disruptors are chemicals that interact with the hormone system to negative effect. They ‘disrupt’ normal processes to cause diseases like vaginal cancer and obesity, reproductive issues like t-shaped uteri and infertility, and developmental abnormalities like spina bifida and cleft palate. These chemicals are ubiquitous in our daily lives, components in everything from toothpaste to microwave popcorn to plastic water bottles. My dissertation looks at the history, science, and regulation of these impactful substances in order to answer the question of how endocrine disruptors appeared, got interpreted by different groups, and what role science played in the process. My analysis reveals that endocrine disruptors followed a unique science policy trajectory in the US, rapidly going from their proposal in 1991 to their federal regulation in 1996, even amid intense and majority scientific disagreement over whether the substances existed at all. That trajectory resulted from the work of a small number of scientist-activists who constructed a concept and category as scientific, social, and regulatory. By playing actors from each sphere against each other and advancing a very specific scientific narrative that fit into a regulatory and social window of opportunity in the 1990s, those scientist-activists made endocrine disruptors a national issue that few could ignore. Those actions resulted in the Endocrine Disruptor Screening Program, a heavily-criticized and ineffective regulatory program. My dissertation tells a story of the past that informs the present. In 2018, the work of researchers, public media, and policymakers in the 1990s continues to play out, evident in the deep scientific division over endocrine disrupting effects and the inability of the European Union to settle on even a definition of endocrine disruptors for regulation purposes.
ContributorsAbboud, Alexis J (Author) / Maienschein, Jane A (Thesis advisor) / Crow, Michael M. (Committee member) / Hurlbut, J. Benjamin (Committee member) / Marchant, Gary E (Committee member) / Arizona State University (Publisher)
Created2018
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This dissertation investigates the relationship between the universal aspirationsof technology and the particularity of place, by way of close participant observation with biotechnology companies in the San Francisco Bay Area. Its central claim is that the aspiration to placelessness in the development of science and technology operates as material configurations,

This dissertation investigates the relationship between the universal aspirationsof technology and the particularity of place, by way of close participant observation with biotechnology companies in the San Francisco Bay Area. Its central claim is that the aspiration to placelessness in the development of science and technology operates as material configurations, modes of subjectivation, and historical conditions particular to places. Following Foucault’s late work in ethics, I conduct a series of sustained investigations into the reflective modes of critique biotechnologists make in thinking of and being in the San Francisco Bay Area. I show the ways the aspiration to placelessness exists in place at four different vantage points: the organization, the city, the broader cultural history of the region, and the practices of self-cultivation undertaken by technologists. Within biotechnology organizations, biological work is digitized and automated only through an intensification of bespoke material infrastructures, physical labor, and tacit institutional knowledge. Biotechnology organizations have come into existence through a history of settler colonial erasure, industrial devastation, post-war industrial decay, and urban renewal in Bay Area industrial suburbs and neighborhoods. A nostalgic imagination of the broader San Francisco Bay Area and its history of counterculture become mobilized as an antidote to the felt lifelessness of these forms of urban renewal and technological order and incorporated back into engineering practice. Finally, the technologist themselves must aspire to placelessness, in ways critiqued by local landless people’s movements who offer an alternative ethic to place in their imperative to gentrifiers to “move home with your parents.” I conclude by reflecting on the ways interlocutors at each of these vantage points are actively exploring the creation of more enduring relationships to place in the face of the unintended but intensified forms of social suffering in zones of technological innovation.
ContributorsHammang, Anne (Author) / Bennett, Gaymon (Thesis advisor) / Hurlbut, J. Benjamin (Committee member) / Frow, Emma (Committee member) / Arizona State University (Publisher)
Created2022