Matching Items (5)
Description
Researchers are often interested in estimating interactions in multilevel models, but many researchers assume that the same procedures and interpretations for interactions in single-level models apply to multilevel models. However, estimating interactions in multilevel models is much more complex than in single-level models. Because uncentered (RAS) or grand mean centered (CGM) level-1 predictors in two-level models contain two sources of variability (i.e., within-cluster variability and between-cluster variability), interactions involving RAS or CGM level-1 predictors also contain more than one source of variability. In this Master’s thesis, I use simulations to demonstrate that ignoring the four sources of variability in a total level-1 interaction effect can lead to erroneous conclusions. I explain how to parse a total level-1 interaction effect into four specific interaction effects, derive equivalencies between CGM and centering within context (CWC) for this model, and describe how the interpretations of the fixed effects change under CGM and CWC. Finally, I provide an empirical example using diary data collected from working adults with chronic pain.
ContributorsMazza, Gina L (Author) / Enders, Craig K. (Thesis advisor) / Aiken, Leona S. (Thesis advisor) / West, Stephen G. (Committee member) / Arizona State University (Publisher)
Created2015
Description
Though the likelihood is a useful tool for obtaining estimates of regression parameters, it is not readily available in the fit of hierarchical binary data models. The correlated observations negate the opportunity to have a joint likelihood when fitting hierarchical logistic regression models. Through conditional likelihood, inferences for the regression and covariance parameters as well as the intraclass correlation coefficients are usually obtained. In those cases, I have resorted to use of Laplace approximation and large sample theory approach for point and interval estimates such as Wald-type confidence intervals and profile likelihood confidence intervals. These methods rely on distributional assumptions and large sample theory. However, when dealing with small hierarchical datasets they often result in severe bias or non-convergence. I present a generalized quasi-likelihood approach and a generalized method of moments approach; both do not rely on any distributional assumptions but only moments of response. As an alternative to the typical large sample theory approach, I present bootstrapping hierarchical logistic regression models which provides more accurate interval estimates for small binary hierarchical data. These models substitute computations as an alternative to the traditional Wald-type and profile likelihood confidence intervals. I use a latent variable approach with a new split bootstrap method for estimating intraclass correlation coefficients when analyzing binary data obtained from a three-level hierarchical structure. It is especially useful with small sample size and easily expanded to multilevel. Comparisons are made to existing approaches through both theoretical justification and simulation studies. Further, I demonstrate my findings through an analysis of three numerical examples, one based on cancer in remission data, one related to the China’s antibiotic abuse study, and a third related to teacher effectiveness in schools from a state of southwest US.
ContributorsWang, Bei (Author) / Wilson, Jeffrey R (Thesis advisor) / Kamarianakis, Ioannis (Committee member) / Reiser, Mark R. (Committee member) / St Louis, Robert (Committee member) / Zheng, Yi (Committee member) / Arizona State University (Publisher)
Created2017
Description
Previous research has shown functional mixed-effects models and traditional mixed-effects models perform similarly when recovering mean and individual trajectories (Fine, Suk, & Grimm, 2019). However, Fine et al. (2019) showed traditional mixed-effects models were able to more accurately recover the underlying mean curves compared to functional mixed-effects models. That project generated data following a parametric structure. This paper extended previous work and aimed to compare nonlinear mixed-effects models and functional mixed-effects models on their ability to recover underlying trajectories which were generated from an inherently nonparametric process. This paper introduces readers to nonlinear mixed-effects models and functional mixed-effects models. A simulation study is then presented where the mean and random effects structure of the simulated data were generated using B-splines. The accuracy of recovered curves was examined under various conditions including sample size, number of time points per curve, and measurement design. Results showed the functional mixed-effects models recovered the underlying mean curve more accurately than the nonlinear mixed-effects models. In general, the functional mixed-effects models recovered the underlying individual curves more accurately than the nonlinear mixed-effects models. Progesterone cycle data from Brumback and Rice (1998) were then analyzed to demonstrate the utility of both models. Both models were shown to perform similarly when analyzing the progesterone data.
ContributorsFine, Kimberly L (Author) / Grimm, Kevin J. (Thesis advisor) / Edward, Mike (Committee member) / O'Rourke, Holly (Committee member) / McNeish, Dan (Committee member) / Arizona State University (Publisher)
Created2019
Description
The comparison of between- versus within-person relations addresses a central issue in psychological research regarding whether group-level relations among variables generalize to individual group members. Between- and within-person effects may differ in magnitude as well as direction, and contextual multilevel models can accommodate this difference. Contextual multilevel models have been explicated mostly for cross-sectional data, but they can also be applied to longitudinal data where level-1 effects represent within-person relations and level-2 effects represent between-person relations. With longitudinal data, estimating the contextual effect allows direct evaluation of whether between-person and within-person effects differ. Furthermore, these models, unlike single-level models, permit individual differences by allowing within-person slopes to vary across individuals. This study examined the statistical performance of the contextual model with a random slope for longitudinal within-person fluctuation data.
A Monte Carlo simulation was used to generate data based on the contextual multilevel model, where sample size, effect size, and intraclass correlation (ICC) of the predictor variable were varied. The effects of simulation factors on parameter bias, parameter variability, and standard error accuracy were assessed. Parameter estimates were in general unbiased. Power to detect the slope variance and contextual effect was over 80% for most conditions, except some of the smaller sample size conditions. Type I error rates for the contextual effect were also high for some of the smaller sample size conditions. Conclusions and future directions are discussed.
A Monte Carlo simulation was used to generate data based on the contextual multilevel model, where sample size, effect size, and intraclass correlation (ICC) of the predictor variable were varied. The effects of simulation factors on parameter bias, parameter variability, and standard error accuracy were assessed. Parameter estimates were in general unbiased. Power to detect the slope variance and contextual effect was over 80% for most conditions, except some of the smaller sample size conditions. Type I error rates for the contextual effect were also high for some of the smaller sample size conditions. Conclusions and future directions are discussed.
ContributorsWurpts, Ingrid Carlson (Author) / Mackinnon, David P (Thesis advisor) / West, Stephen G. (Committee member) / Grimm, Kevin J. (Committee member) / Suk, Hye Won (Committee member) / Arizona State University (Publisher)
Created2016
Description
Accurate data analysis and interpretation of results may be influenced by many potential factors. The factors of interest in the current work are the chosen analysis model(s), the presence of missing data, and the type(s) of data collected. If analysis models are used which a) do not accurately capture the structure of relationships in the data such as clustered/hierarchical data, b) do not allow or control for missing values present in the data, or c) do not accurately compensate for different data types such as categorical data, then the assumptions associated with the model have not been met and the results of the analysis may be inaccurate. In the presence of clustered
ested data, hierarchical linear modeling or multilevel modeling (MLM; Raudenbush & Bryk, 2002) has the ability to predict outcomes for each level of analysis and across multiple levels (accounting for relationships between levels) providing a significant advantage over single-level analyses. When multilevel data contain missingness, multilevel multiple imputation (MLMI) techniques may be used to model both the missingness and the clustered nature of the data. With categorical multilevel data with missingness, categorical MLMI must be used. Two such routines for MLMI with continuous and categorical data were explored with missing at random (MAR) data: a formal Bayesian imputation and analysis routine in JAGS (R/JAGS) and a common MLM procedure of imputation via Bayesian estimation in BLImP with frequentist analysis of the multilevel model in Mplus (BLImP/Mplus). Manipulated variables included interclass correlations, number of clusters, and the rate of missingness. Results showed that with continuous data, R/JAGS returned more accurate parameter estimates than BLImP/Mplus for almost all parameters of interest across levels of the manipulated variables. Both R/JAGS and BLImP/Mplus encountered convergence issues and returned inaccurate parameter estimates when imputing and analyzing dichotomous data. Follow-up studies showed that JAGS and BLImP returned similar imputed datasets but the choice of analysis software for MLM impacted the recovery of accurate parameter estimates. Implications of these findings and recommendations for further research will be discussed.
ested data, hierarchical linear modeling or multilevel modeling (MLM; Raudenbush & Bryk, 2002) has the ability to predict outcomes for each level of analysis and across multiple levels (accounting for relationships between levels) providing a significant advantage over single-level analyses. When multilevel data contain missingness, multilevel multiple imputation (MLMI) techniques may be used to model both the missingness and the clustered nature of the data. With categorical multilevel data with missingness, categorical MLMI must be used. Two such routines for MLMI with continuous and categorical data were explored with missing at random (MAR) data: a formal Bayesian imputation and analysis routine in JAGS (R/JAGS) and a common MLM procedure of imputation via Bayesian estimation in BLImP with frequentist analysis of the multilevel model in Mplus (BLImP/Mplus). Manipulated variables included interclass correlations, number of clusters, and the rate of missingness. Results showed that with continuous data, R/JAGS returned more accurate parameter estimates than BLImP/Mplus for almost all parameters of interest across levels of the manipulated variables. Both R/JAGS and BLImP/Mplus encountered convergence issues and returned inaccurate parameter estimates when imputing and analyzing dichotomous data. Follow-up studies showed that JAGS and BLImP returned similar imputed datasets but the choice of analysis software for MLM impacted the recovery of accurate parameter estimates. Implications of these findings and recommendations for further research will be discussed.
ContributorsKunze, Katie L (Author) / Levy, Roy (Thesis advisor) / Enders, Craig K. (Committee member) / Thompson, Marilyn S (Committee member) / Arizona State University (Publisher)
Created2016