2026-05-20T11:33:27Zhttps://keep.lib.asu.edu/oai/requestoai:keep.lib.asu.edu:node-2024872025-09-09T20:36:45Zoai_pmh:alloai_pmh:repo_items202487
https://hdl.handle.net/2286/R.2.N.202487
2024-08-20
Andersun, Eboni E.
Pinteric, Aubrey
Text
<p>In July 2011, Makoto Ohnishi and colleagues published the article "Is Neisseria gonorrhoeae Initiating a Future Era of Untreatable Gonorrhea?: Detailed Characterization of the First Strain with High-Level Resistance to Ceftriaxone," hereafter, "Untreatable Gonorrhea," in the journal Antimicrobial Agents and Chemotherapy. Gonorrhea is a sexually transmitted disease, or STD, caused by the bacterium Neisseria gonorrhoeae. In 2009, Ohnishi and a few of his co-authors found the first ceftriaxone-resistant strain of gonorrhea, called H041. That strain demonstrated resistance to ceftriaxone, one of the last remaining and effective first-line antibiotic treatment drugs forN. gonorrhoeae. In "Untreatable Gonorrhea," Ohnishi and Colleagues confirm that the H041 strain is resistant to ceftriaxone and analyze the bacterium's mechanism of resistance. "Untreatable Gonorrhea" was one of the first publications to characterize the H041strain and highlights a need for global public health interventions to prevent the rapid spread of gonorrhea.</p>
Gonorrhea
Sexually Transmitted Diseases
Sexually Transmitted Diseases
Drug resistance in microorganisms
Antibiotics
Sulfonamides
Tetracycline
Unemo, Magnus
Ohnishi, Makoto
"Is Neisseria gonorrhoeae Initiating a Future Era of Untreatable Gonorrhea? Detailed Characterization of the First Strain with High-Level Resistance to Ceftriaxone"(2011), by Makoto Ohnishi, Daniel Golparian, Ken Shimuta, Takeshi Saika, et al.