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173832 https://hdl.handle.net/10776/2291 2011-08-16 eng Zhang, Mark Arizona State University. School of Life Sciences. Center for Biology and Society. Embryo Project Encyclopedia. Arizona Board of Regents open access http://creativecommons.org/licenses/by-nc-sa/3.0/ John Hilton Edwards first described the symptoms of the genetic disorder known as Trisomy 18 - one of the most common forms of trisomy, which occurs when cells have an extra copy of a chromosome, in humans - in 1960. Trisomy 18, also known as Edwards Syndrome, occurs approximately once per 6000 live births and is second in frequency only to Trisomy 21, or Down's Syndrome, as an autosomal trisomy. Trisomy 18 causes substantial developmental problems in utero. Trisomy fetus Congenital Disorders Human Development Trisomy 18 (Edwards Syndrome)