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oai:keep.lib.asu.edu:node-1291602025-09-16T16:34:45Zoai_pmh:alloai_pmh:repo_items

129160 https://hdl.handle.net/2286/R.I.35653 <p>Karmin, Monika; Saag, Lauri; Vicente, Mario; et.al. (2015). A recent bottleneck of Y chromosome diversity coincides with a global change in culture. GENOME RESEARCH, 25(4), 459-466. http://dx.doi.org/10.1101/gr.186684.114</p> 10.1101/gr.186684.114 1088-9051 1549-5469 http://rightsstatements.org/vocab/InC/1.0/ open access http://creativecommons.org/licenses/by-nc-nd/4.0 2015-04-01 8 pages eng Karmin, Monika Saag, Lauri Vicente, Mario Wilson Sayres, Melissa Jarve, Mari Talas, Ulvi Gerst Rootsi, Siiri Ilumaee, Anne-Mai Maegi, Reedik Mitt, Mario Pagani, Luca Puurand, Tarmo Faltyskova, Zuzana Clemente, Florian Cardona, Alexia Metspalu, Ene Sahakyan, Hovhannes Yunusbayev, Bayazit Hudjashov, Georgi DeGiorgio, Michael Loogvaeli, Eva-Liis Eichstaedt, Christina Eelmets, Mikk Chaubey, Gyaneshwer Tambets, Kristiina Litvinov, Sergei Mormina, Maru Xue, Yali Ayub, Qasim Zoraqi, Grigor Korneliussen, Thorfinn Sand Akhatova, Farida Lachance, Joseph Tishkoff, Sarah Momynaliev, Kuvat Ricaut, Francois-Xavier Kusuma, Pradiptajati Razafindrazaka, Harilanto Pierron, Denis Cox, Murray P. Sultana, Gazi Nurun Nahar Willerslev, Rane Muller, Craig Westaway, Michael Lambert, David Skaro, Vedrana Kovacevic, Lejla Turdikulova, Shahlo Dalimova, Dilbar Khusainova, Rita Trofimova, Natalya Akhmetova, Vita Khidiyatova, Irina Lichman, Daria V. Isakova, Jainagul Pocheshkhova, Nymadawa Mihailov, Evelin Seng, Joseph Wee Tien Evseeva, Irina Migliano, Andrea Bamberg Abdullah, Syafiq Andriadze, George Primorac, Dragan Atramentova, Lubov Utevska, Olga Yepiskoposyan, Levon Marjanovic, Damir Kushniarevich, Alena Behar, Doron M. Gilissen, Christian Vissers, Lisenka Veltman, Joris Balanovska, Elena Derenko, Miroslava Malyarchuk, Boris Metspalu, Andres Federova, Sardana Eriksson, Anders Manica, Andrea Mendez, Fernando L. Karafet, Tatiana M. Veeramah, Krishna R. Bradman, Neil Hammer, Michael F. Osipova, Ludmila P. Balanovsky, Oleg Khusnutdinova, Elza K. Johnsen, Knut Remm, Maido Thomas, Mark G. Tyler-Smith, Chris Underhill, Peter A. Willerslev, Eske Nielsen, Rasmus Metspalu, Mait Villems, Richard Kivisild, Toomas College of Liberal Arts and Sciences <p>It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50–100 thousand yr ago (kya). Here, we present a study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples. Applying ancient DNA calibration, we date the Y-chromosomal most recent common ancestor (MRCA) in Africa at 254 (95% CI 192–307) kya and detect a cluster of major non-African founder haplogroups in a narrow time interval at 47–52 kya, consistent with a rapid initial colonization model of Eurasia and Oceania after the out-of-Africa bottleneck. In contrast to demographic reconstructions based on mtDNA, we infer a second strong bottleneck in Y-chromosome lineages dating to the last 10 ky. We hypothesize that this bottleneck is caused by cultural changes affecting variance of reproductive success among males.</p> A Recent Bottleneck of Y Chromosome Diversity Coincides With a Global Change in Culture