Description

Quiescin sulfhydryl oxidase 1 (QSOX1) is an enzyme that catalyzes disulfide bond formation by oxidizing two free sulfhydryl groups. QSOX1 consists of a thioredoxin (Trx) and an ERV (essential for

Quiescin sulfhydryl oxidase 1 (QSOX1) is an enzyme that catalyzes disulfide bond formation by oxidizing two free sulfhydryl groups. QSOX1 consists of a thioredoxin (Trx) and an ERV (essential for respiration and viability)/ALR (augmenter of liver regeneration) domain which each contain CxxC motifs that work to bind to substrates and shuttle electrons to a flavin adenine dinucleotide (FAD) cofactor that accepts the electrons and reduces molecular oxygen to hydrogen peroxide.

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Date Created
  • 2019
Resource Type
  • Text
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    Note
    • Partial requirement for: M.S., Arizona State University, 2019
      Note type
      thesis
    • Includes bibliographical references (pages 31-34)
      Note type
      bibliography
    • Field of study: Molecular and cellular biology

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    by Calvin John Koelbel

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