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  4. Is apple cider vinegar effective for reducing heartburn symptoms related to gastroesophageal reflux disease?
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Is apple cider vinegar effective for reducing heartburn symptoms related to gastroesophageal reflux disease?

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Description

Drinking vinegar is a popularly discussed remedy for relieving heartburn symptom, as can be read on many websites; however, there has been no scientific research or theory to support its efficacy. This randomized, placebo-controlled, double-blind, cross-over research study tested the efficacy of the organic apple cider vinegar, with mother, on alleviation of the heartburn symptom related to Gastro-esophageal reflux disease (GERD). A minimum of one week separated the four trial arms: chili (placebo), antacid after chili meal (positive control), vinegar added to chili, and diluted vinegar after chili meal. Twenty grams of vinegar were used in both vinegar treatments, and 10 grams of liquid antacid were used in the antacid trial. A five-point Likert scale and a 10-cm visual analogue scale (VAS) were used to assess heartburn severity during a 120 minutes testing time. Seven of 15 recruited subjects' data was usable for statistical analysis (age: 39.6 ± 12.2 y, body mass index (BMI): 29.4 ± 4.2 kg/m2, waist circumference: 36.4 ± 4.1 inch). There was no statistically significant difference among the mean and incremental area-under-the-curve (iAUC) heartburn scores among different trials (Likert scale questionnaire p= .259, VAS questionnaire p= .659, iAUC Likert scale p= .184, iAUC VAS p= .326). Seven participants were further divided into antacid responder (n=4) and antacid non-responder groups (n=3). Likert scale mean heartburn score and iAUC data in antacid responder group had significant finding (p= .034 and p= .017 respectively). The significance lay between antacid and 'vinegar added to chili' trials. Effect size was also used to interpret data due to the small sample size: Likert scale: mean heartburn score= .444, iAUC= .425; VAS mean heartburn score= .232, iAUC .611. Effect size for antacid responder group was Likert scale: mean heartburn score= .967, iAUC= .936. Future research is needed to examine whether ingesting organic vinegar benefits alleviation of heartburn symptom related to GERD for people who do not respond well to antacid.

Date Created
2016
Contributors
  • Yeh, Zoe (Author)
  • Johnston, Carol (Thesis advisor)
  • Mayol-Kreiser, Sandra (Committee member)
  • Lespron, Christy (Committee member)
  • Arizona State University (Publisher)
Topical Subject
  • Nutrition
  • acid reflux
  • apple cider vinegar
  • GERD
  • Heartburn
  • remedy
  • Vinegar
  • Gastroesophageal reflux
  • Heartburn
  • Cider vinegar--Physiological effect.
  • Cider vinegar
  • Cider vinegar--Therapeutic use.
  • Cider vinegar
Resource Type
Text
Genre
Masters Thesis
Academic theses
Extent
viii, 103 pages : color illustrations
Language
eng
Copyright Statement
In Copyright
Reuse Permissions
All Rights Reserved
Primary Member of
ASU Electronic Theses and Dissertations
Peer-reviewed
No
Open Access
No
Handle
https://hdl.handle.net/2286/R.I.37045
Statement of Responsibility
by Zoe Yeh
Description Source
Retrieved on May 10, 2016
Level of coding
full
Note
Partial requirement for: M.S., Arizona State University, 2016
Note type
thesis
Includes bibliographical references (pages 67-76)
Note type
bibliography
Field of study: Nutrition
System Created
  • 2016-04-01 08:00:38
System Modified
  • 2021-08-30 01:25:06
  •     
  • 1 year 6 months ago
Additional Formats
  • OAI Dublin Core
  • MODS XML

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