Immunosignaturing is a new immunodiagnostic technology that uses random-sequence peptide microarrays to profile the humoral immune response. Though the peptides have little sequence homology to any known protein, binding of serum antibodies may be detected, and the pattern correlated to disease states. The aim of my dissertation is to analyze the factors affecting the binding patterns using monoclonal antibodies and determine how much information may be extracted from the sequences.
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- Partial requirement for: Ph.D., Arizona State University, 2011Note typethesis
- Includes bibliographical referencesNote typebibliography
- Field of study: Molecular and cellular biology