Description
Transgene expression in mammalian cells has been shown to meet resistance in the form of silencing due to chromatin buildup within the cell. Interactions of proteins with chromatin modulate gene expression profiles. Synthetic Polycomb transcription factor (PcTF) variants have the potential to reactivate these silence transgenes as shown in Haynes & Silver 2011.
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Contributors
- Gardner, Cameron Lee (Author)
- Haynes, Karmella (Thesis director)
- Stabenfeldt, Sarah (Committee member)
- Barrett, The Honors College (Contributor)
- Department of Finance (Contributor)
- Harrington Bioengineering Program (Contributor)
Date Created
The date the item was original created (prior to any relationship with the ASU Digital Repositories.)
2015-05
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