Description

BACKGROUND: During development both Hebbian and homeostatic mechanisms regulate synaptic efficacy, usually working in opposite directions in response to neuronal activity. Homeostatic plasticity has often been investigated by assaying changes

BACKGROUND: During development both Hebbian and homeostatic mechanisms regulate synaptic efficacy, usually working in opposite directions in response to neuronal activity. Homeostatic plasticity has often been investigated by assaying changes in spontaneous synaptic transmission resulting from chronic circuit inactivation. However, effects of inactivation on evoked transmission have been less frequently reported. Importantly, contributions from the effects of circuit inactivation and reactivation on synaptic efficacy have not been individuated.

Reuse Permissions
  • application/pdf

    Download count: 0

    Details

    Contributors
    Date Created
    • 2013-09-22
    Resource Type
  • Text
  • Collections this item is in
    Identifier
    • Digital object identifier: 10.1186/1756-6606-6-38
    • Identifier Type
      International standard serial number
      Identifier Value
      1756-6606

    Citation and reuse

    Cite this item

    This is a suggested citation. Consult the appropriate style guide for specific citation guidelines.

    Gerkin, R. C., Nauen, D. W., Xu, F., & Bi, G.-Q. (2013). Homeostatic regulation of spontaneous and evoked synaptic transmission in two steps. Molecular Brain, 6(1), 38. doi:10.1186/1756-6606-6-38

    Machine-readable links