Description

Pathogen reduction is a viable approach to ensure the continued safety of the blood supply against emerging pathogens. However, the currently licensed pathogen reduction techniques are ineffective against non-enveloped viruses

Pathogen reduction is a viable approach to ensure the continued safety of the blood supply against emerging pathogens. However, the currently licensed pathogen reduction techniques are ineffective against non-enveloped viruses such as hepatitis A virus, and they introduce chemicals with concerns of side effects which prevent their widespread use. In this report, we demonstrate the inactivation of both enveloped and non-enveloped viruses in human plasma using a novel chemical-free method, a visible ultrashort pulsed laser.

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Date Created
  • 2014-11-05
Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.1371/journal.pone.0111673
    • Identifier Type
      International standard serial number
      Identifier Value
      1045-3830
    • Identifier Type
      International standard serial number
      Identifier Value
      1939-1560

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    This is a suggested citation. Consult the appropriate style guide for specific citation guidelines.

    Tsen S-WD, Kingsley DH, Kibler K, Jacobs B, Sizemore S, et al. (2014) Pathogen Reduction in Human Plasma Using an Ultrashort Pulsed Laser. PLoS ONE 9(11): e111673. doi:10.1371/journal.pone.0111673

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