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Background
Tissue-specific RNA plasticity broadly impacts the development, tissue identity and adaptability of all organisms, but changes in composition, expression levels and its impact on gene regulation in different somatic

Background
Tissue-specific RNA plasticity broadly impacts the development, tissue identity and adaptability of all organisms, but changes in composition, expression levels and its impact on gene regulation in different somatic tissues are largely unknown. Here we developed a new method, polyA-tagging and sequencing (PAT-Seq) to isolate high-quality tissue-specific mRNA from Caenorhabditis elegans intestine, pharynx and body muscle tissues and study changes in their tissue-specific transcriptomes and 3’UTRomes.
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    Date Created
    • 2015-01-20
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.1186/s12915-015-0116-6
    • Identifier Type
      International standard serial number
      Identifier Value
      1741-7007
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    Blazie, S. M., Babb, C., Wilky, H., Rawls, A., Park, J. G., & Mangone, M. (2015). Comparative RNA-Seq analysis reveals pervasive tissue-specific alternative polyadenylation in Caenorhabditis elegans intestine and muscles. BMC Biology, 13(1), 4. doi:10.1186/s12915-015-0116-6

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