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Background
Heterogeneity within cell populations is relevant to the onset and progression of disease, as well as development and maintenance of homeostasis. Analysis and understanding of the roles of heterogeneity

Background
Heterogeneity within cell populations is relevant to the onset and progression of disease, as well as development and maintenance of homeostasis. Analysis and understanding of the roles of heterogeneity in biological systems require methods and technologies that are capable of single cell resolution. Single cell gene expression analysis by RT-qPCR is an established technique for identifying transcriptomic heterogeneity in cellular populations, but it generally requires specialized equipment or tedious manipulations for cell isolation.
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    Date Created
    • 2014-05-08
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.1186/1480-9222-16-9
    • Identifier Type
      International standard serial number
      Identifier Value
      1480-9222
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    Yaron, J. R., Ziegler, C. P., Tran, T. H., Glenn, H. L., & Meldrum, D. R. (2014). A convenient, optimized pipeline for isolation, fluorescence microscopy and molecular analysis of live single cells. Biological Procedures Online, 16(1), 9. doi:10.1186/1480-9222-16-9

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