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Leucine-responsive regulatory protein (Lrp) is known to be an indirect activator of type 1 fimbriae synthesis in Salmonella enterica serovar Typhimurium via direct regulation of FimZ, a direct positive regulator

Leucine-responsive regulatory protein (Lrp) is known to be an indirect activator of type 1 fimbriae synthesis in Salmonella enterica serovar Typhimurium via direct regulation of FimZ, a direct positive regulator for type 1 fimbriae production. Using RT-PCR, we have shown previously that fimA transcription is dramatically impaired in both lrp-deletion (Δlrp) and constitutive-lrp expression (lrp[superscript C]) mutant strains. In this work, we used chromosomal P[subscript fimA]-lacZ fusions and yeast agglutination assays to confirm and extend our previous results.

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    Date Created
    • 2011-10-28
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.1371/journal.pone.0026896
    • Identifier Type
      International standard serial number
      Identifier Value
      1045-3830
    • Identifier Type
      International standard serial number
      Identifier Value
      1939-1560

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    Baek, C., Kang, H., Roland, K. L., & Curtiss, R. (2011). Lrp Acts as Both a Positive and Negative Regulator for Type 1 Fimbriae Production in Salmonella enterica Serovar Typhimurium. PLoS ONE, 6(10). doi:10.1371/journal.pone.0026896

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