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Vitamin D receptor (VDR) is a substrate for modification with small ubiquitin-like modifier (SUMO). To further assess the role of reversible SUMOylation within the vitamin D hormonal response, we evaluated

Vitamin D receptor (VDR) is a substrate for modification with small ubiquitin-like modifier (SUMO). To further assess the role of reversible SUMOylation within the vitamin D hormonal response, we evaluated the effects of sentrin/SUMO-specific proteases (SENPs) that can function to remove small ubiquitin-like modifier (SUMO) from target proteins upon the activities of VDR and related receptors.

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    Date Created
    • 2014-02-20
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.1371/journal.pone.0089506
    • Identifier Type
      International standard serial number
      Identifier Value
      1045-3830
    • Identifier Type
      International standard serial number
      Identifier Value
      1939-1560

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    Lee, W., Jena, S., Doherty, D., Ventakesh, J., Schimdt, J., Furmick, J., . . . Thompson, P. D. (2014). Sentrin/SUMO Specific Proteases as Novel Tissue-Selective Modulators of Vitamin D Receptor-Mediated Signaling. PLoS ONE, 9(2). doi:10.1371/journal.pone.0089506

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