Serum Amyloid A (SAA) is an acute phase protein complex consisting of several abundant isoforms. The N- terminus of SAA is critical to its function in amyloid formation. SAA is frequently truncated, either missing an arginine or an arginine-serine dipeptide, resulting in isoforms that may influence the capacity to form amyloid. However, the relative abundance of truncated SAA in diabetes and chronic kidney disease is not known.
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- Digital object identifier: 10.1371/journal.pone.0115320
- Identifier TypeInternational standard serial numberIdentifier Value1045-3830
- Identifier TypeInternational standard serial numberIdentifier Value1939-1560
- The article is published at http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0115320, opens in a new window
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Yassine, H. N., Trenchevska, O., He, H., Borges, C. R., Nedelkov, D., Mack, W., . . . Nelson, R. W. (2015). Serum Amyloid A Truncations in Type 2 Diabetes Mellitus. Plos One, 10(1). doi:10.1371/journal.pone.0115320