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The rise in antibiotic resistance has led to an increased research focus on discovery of new antibacterial candidates. While broad-spectrum antibiotics are widely pursued, there is evidence that resistance arises

The rise in antibiotic resistance has led to an increased research focus on discovery of new antibacterial candidates. While broad-spectrum antibiotics are widely pursued, there is evidence that resistance arises in part from the wide spread use of these antibiotics. Our group has developed a system to produce protein affinity agents, called synbodies, which have high affinity and specificity for their target. In this report, we describe the adaptation of this system to produce new antibacterial candidates towards a target bacterium.

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    Date Created
    • 2013-01-23
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  • Text
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    Identifier
    • Digital object identifier: 10.1371/journal.pone.0054162
    • Identifier Type
      International standard serial number
      Identifier Value
      1045-3830
    • Identifier Type
      International standard serial number
      Identifier Value
      1939-1560

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    Domenyuk, V., Loskutov, A., Johnston, S. A., & Diehnelt, C. W. (2013). A Technology for Developing Synbodies with Antibacterial Activity. PLoS ONE, 8(1). doi:10.1371/journal.pone.0054162

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