Description

Levels of nucleotide diversity vary greatly across the genomes of most species owing to multiple factors. These include variation in the underlying mutation rates, as well as the effects of

Levels of nucleotide diversity vary greatly across the genomes of most species owing to multiple factors. These include variation in the underlying mutation rates, as well as the effects of both direct and linked selection. Fundamental to interpreting the relative importance of these forces is the common observation of a strong positive correlation between nucleotide diversity and recombination rate. While indeed observed in humans, the interpretation of this pattern has been difficult in the absence of high-quality polymorphism data and recombination maps in closely related species.

Reuse Permissions
  • application/pdf

    Download count: 0

    Details

    Contributors
    Date Created
    • 2016-09-27
    Resource Type
  • Text
  • Collections this item is in
    Identifier
    • Digital object identifier: 10.1093/gbe/evw240
    • Identifier Type
      International standard serial number
      Identifier Value
      1759-6653
    Note

    Citation and reuse

    Cite this item

    This is a suggested citation. Consult the appropriate style guide for specific citation guidelines.

    Pfeifer, S. P., & Jensen, J. D. (2016). The Impact of Linked Selection in Chimpanzees: A Comparative Study. Genome Biology and Evolution, 8(10), 3202-3208. doi:10.1093/gbe/evw240

    Machine-readable links