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The maternal separation (MS) paradigm is an animal model of early life stress. Animals subjected to MS during the first 2 weeks of life display altered behavioral and neuroendocrinological stress

The maternal separation (MS) paradigm is an animal model of early life stress. Animals subjected to MS during the first 2 weeks of life display altered behavioral and neuroendocrinological stress responses as adults. MS also produces altered responsiveness to and self-administration (SA) of various drugs of abuse including cocaine, ethanol, and amphetamine. However, no studies have yet examined the effects of MS on methamphetamine (METH) SA.

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    Date Created
    • 2013-06-17
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.3389/fpsyt.2013.00055
    • Identifier Type
      International standard serial number
      Identifier Value
      1664-0640

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    Lewis, C. R., Staudinger, K., Scheck, L., & Olive, M. F. (2013). The Effects of Maternal Separation on Adult Methamphetamine Self-Administration, Extinction, Reinstatement, and MeCP2 Immunoreactivity in the Nucleus Accumbens. Frontiers in Psychiatry, 4. doi:10.3389/fpsyt.2013.00055

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