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Narita 104 virus is a human pathogen belonging to the norovirus (family Caliciviridae) genogroup II. Noroviruses cause epidemic gastroenteritis worldwide. To explore the potential of developing a plant-based vaccine, a

Narita 104 virus is a human pathogen belonging to the norovirus (family Caliciviridae) genogroup II. Noroviruses cause epidemic gastroenteritis worldwide. To explore the potential of developing a plant-based vaccine, a plant optimized gene encoding Narita 104 virus capsid protein (NaVCP) was expressed transiently in Nicotiana benthamiana using a tobacco mosaic virus expression system. NaVCP accumulated up to approximately 0.3 mg/g fresh weight of leaf at 4 days postinfection.

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    Date Created
    • 2014-05-11
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.1155/2014/807539
    • Identifier Type
      International standard serial number
      Identifier Value
      2314-6133
    • Identifier Type
      International standard serial number
      Identifier Value
      2314-6141

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    Mathew, L. G., Herbst-Kralovetz, M. M., & Mason, H. S. (2014). Norovirus Narita 104 Virus-Like Particles Expressed inNicotiana benthamianaInduce Serum and Mucosal Immune Responses. BioMed Research International, 2014, 1-9. doi:10.1155/2014/807539

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