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Pathogenic and nonpathogenic species of bacteria and fungi release membrane vesicles (MV), containing proteins, polysaccharides, and lipids, into the extracellular milieu. Previously, we demonstrated that several mycobacterial species, including bacillus

Pathogenic and nonpathogenic species of bacteria and fungi release membrane vesicles (MV), containing proteins, polysaccharides, and lipids, into the extracellular milieu. Previously, we demonstrated that several mycobacterial species, including bacillus Calmette-Guerin (BCG) and Mycobacterium tuberculosis, release MV containing lipids and proteins that subvert host immune response in a Toll-like receptor 2 (TLR2)-dependent manner (R. Prados-Rosales et al., J. Clin. Invest. 121:1471–1483, 2011, doi:10.1172/JCI44261).

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    Date Created
    • 2014-09-30
    Resource Type
  • Text
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    Identifier
    • Digital object identifier: 10.1128/mBio.01921-14
    • Identifier Type
      International standard serial number
      Identifier Value
      2150-7511
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    Prados-Rosales, R., Carreno, L. J., Batista-Gonzalez, A., Baena, A., Venkataswamy, M. M., Xu, J., . . . Casadevall, A. (2014). Mycobacterial Membrane Vesicles Administered Systemically in Mice Induce a Protective Immune Response to Surface Compartments of Mycobacterium tuberculosis. MBio, 5(5). doi:10.1128/mbio.01921-14

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