Description

5-HT[subscript 1B] receptors (5-HT[subscript 1B]Rs) modulate behavioral effects of cocaine. Here we examined the effects of the 5-HT[subscript 1B]R agonist 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine (CP94253) on spontaneous and cocaine-induced locomotion and on cocaine-primed

5-HT[subscript 1B] receptors (5-HT[subscript 1B]Rs) modulate behavioral effects of cocaine. Here we examined the effects of the 5-HT[subscript 1B]R agonist 5-propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine (CP94253) on spontaneous and cocaine-induced locomotion and on cocaine-primed reinstatement of conditioned place preference (CPP) in male mice given daily repeated injections of either saline or cocaine (15 mg/kg, IP) for 20 days. In the locomotor activity experiment, testing occurred both 1 and 20 days after the final injection.

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    Date Created
    • 2017-10-10
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    Identifier
    • Digital object identifier: 10.3389/fnsys.2017.00073
    • Identifier Type
      International standard serial number
      Identifier Value
      1662-5137

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    Der-Ghazarian, T. S., Call, T., Scott, S. N., Dai, K., Brunwasser, S. J., Noudali, S. N., . . . Neisewander, J. L. (2017). Effects of a 5-HT1B Receptor Agonist on Locomotion and Reinstatement of Cocaine-Conditioned Place Preference after Abstinence from Repeated Injections in Mice. Frontiers in Systems Neuroscience, 11. doi:10.3389/fnsys.2017.00073

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